Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances …
Background/Objectives: The objective of this exploratory study was to test the hypothesis that endometriosis is associated with altered abundance and cellular location of nuclear progesterone receptor (PR) isoforms in eutopic …
Endometriosis is a chronic, systemic gynecological disorder that affects 190 million women worldwide. Current treatments consist of hormonal suppression and surgical excision; however, both have considerable side effects and a …
Gynecological conditions including endometriosis, polyendocrine metabolic ovarian syndrome and malignancies cause widespread chronic morbidity and infertility, yet translating genetic discoveries into biological mechanisms remains challenging. We propose a framework integrating …
Endometriosis is a debilitating, estrogen-dependent gynecological disorder characterized by profound diagnostic delays due to clinical reliance on invasive laparoscopy. Developing noninvasive, point-of-care biomarker assessment remains a critical yet unmet medical …
Early pregnancy bleeding is a common pregnancy complication, yet its genetic basis and potential links with psychiatric traits remain poorly understood. This study aimed to characterize the shared genetic architecture …
Background and Objectives: Endometriosis is a chronic inflammatory disease associated with impaired fertility, but the extent to which its systemic inflammatory profile differs from that observed in infertile women without …
FemTech continues to evolve and advance despite persistent research and funding gaps. In this News and Perspectives article, JMIR Correspondent Jenny Castillo Cato reports on an innovative, cross-disciplinary research project …
The double-stapled anastomosis technique is widely considered the standard approach for colorectal anastomosis after anterior rectal resection. Recently, the single-stapled anastomosis technique has gained attention because it may reduce potential …
Endometriosis is a disease where cells similar to those of the uterine lining grow outside of the uterus, embedding into tissues and organs in the abdominal cavity, forming lesions and …