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A large-scale genome-wide association study on female genital tract polyps highlights role of DNA repair, cell proliferation, and cell growth.

Can a large-scale genome-wide association study (GWAS) meta-analysis identify genomic risk loci and likely involved genes for female genital tract (FGT) polyps, provide insights into the biological mechanism underlying their …

Published: Feb. 22, 2025, midnight
Molecular Basis of Impaired Decidualization in the Eutopic Endometrium of Endometriosis Patients.

Endometriosis is a chronic gynecological disorder characterized by the presence of endometrial tissue outside the uterine cavity. A common feature of this pathology is the impaired decidualization of endometrial stromal …

Published: Feb. 21, 2025, midnight
Perturbations of the endometrial immune microenvironment in endometriosis and adenomyosis: their impact on reproduction and pregnancy.

The impact of endometriosis and adenomyosis on reproduction and pregnancy is significant, with both conditions linked to increased rates of infertility, poor ovarian function in women with endometriosis, and elevated …

Published: Feb. 18, 2025, midnight
Association between blood heavy metals exposure with uterine fibroids among American women: a cross-sectional analysis from NHANES data.

Excessive exposure to heavy metals has been linked to various health problems, including organ damage, neurological disorders, and reproductive and developmental abnormalities. However, the relationship between heavy metals exposure and …

Published: Feb. 18, 2025, midnight
Reproductive tract microbiome dysbiosis associated with gynecological diseases.

Female health and the microbiota of the reproductive tract are closely associated. The research scope on reproductive tract microbiota extends from the vaginal to the upper reproductive tract and from …

Published: Feb. 18, 2025, midnight
The integral roles of the TGFβ signaling pathway in uterine function and disease.

The uterus is a complex organ that requires precise signaling networks to mediate functions necessary for homeostasis and reproductive processes. The transforming growth factor β (TGFβ) superfamily regulates integral signaling …

Published: Feb. 14, 2025, midnight
Pelvic pain & endometriosis: the development of a patient-centred e-health resource for those affected by endometriosis-associated dyspareunia.

We recognized a paucity of accessible, evidence-based, empowering patient-centred resources for those with endometriosis-associated dyspareunia. Affecting more than 50% of people with endometriosis, dyspareunia can significantly impact relationships, chronic pain …

Published: Feb. 13, 2025, midnight
Curcumol inhibits endometrial cell invasion through the NF-κB pathway in rats with endometriosis.

Curcumol (Cur) has been found to be useful in improving Endometriosis (EMS), however its mechanism of action is still not completely understood. Based on this, the current study was carried …

Published: Feb. 12, 2025, 12:13 a.m.
Unraveling the role of lncRNA in Endometriosis-Associated immune system Dysregulation: Exploring the intricate immunological changes and disrupted signaling pathways.

A chronic illness known as endometriosis impacts women who are of reproductive maturity. It may be a factor in fertility problems, breast or ovarian cancer, asthma, cardiovascular illness, or pelvic …

Published: Feb. 5, 2025, midnight
CD56-Positive NK Cells and CD138-Positive Plasma Cells in Basal Decidua of Term Placentas in Singleton Pregnancies After Assisted Reproductive Technology Treatment of Endometriosis-Related Infertility.

A eutopic endometrium in endometriosis shows altered immune responses, including abnormalities of NK cells and expression of plasma cells, related to reproductive issues. This study investigated the counts of CD56-positive …

Published: Feb. 5, 2025, midnight
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