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Association between urinary heavy metals, phthalates, phytoestrogens, and polycyclic aromatic hydrocarbons and endometriosis: A cross-sectional study from NHANES 1999 to 2016.

Research on the association between urinary heavy metals, phthalates, phytoestrogens (PEs), polycyclic aromatic hydrocarbons (PAHs), and endometriosis (EM) is limited. Data were from the National Health and Nutrition Examination Survey …

Published: June 17, 2026, midnight
NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals.

Reliable non-invasive biomarkers for endometriosis remain unavailable in routine practice, and their translational value depends on performance in symptomatic referral populations rather than only against healthy controls. We evaluated Nuclear …

Published: June 17, 2026, midnight
PRT-064040: A nasal spray of novel, potent, and selective calcitonin gene-related peptide receptor antagonist for migraine.

Calcitonin gene-related peptide (CGRP), a neuropeptide, has been implicated in autoimmune diseases, endometriosis, tumors, and primary headaches, including migraine. The development of a novel, fast-acting CGRP receptor antagonist administered via …

Published: June 17, 2026, midnight
Interleukin-17A as a key driver for cell migration, proliferation, inflammation, and nerve infiltration in deep endometriosis.

Deep endometriosis (DE) is the most severe subtype of endometriosis, marked by aggressive cellular behavior and debilitating pain. However, the molecular mechanisms underlying DE pathogenesis remain poorly understood. In this …

Published: June 15, 2026, midnight
RNF34 restrains endometriosis through SREBP1-dependent metabolic-immune crosstalk.

Endometriosis is a chronic inflammatory disease with cancer-like features, yet the mechanisms linking metabolic dysregulation to immune remodeling during lesion progression remain poorly understood. Here, we identify the ubiquitin E3 …

Published: June 13, 2026, midnight
Diagnostic Accuracy of Hysterosalpingography Compared With Laparoscopy in Assessing Tubal Patency Among Subfertile Women: A Retrospective Cohort Study.

Background Fallopian tube pathology accounts for approximately one-third of female factor subfertility. The National Institute for Health and Care Excellence (NICE) Fertility Guidelines (CG156) recommend hysterosalpingography (HSG) as the first-line …

Published: June 13, 2026, midnight
Updates in ultrasound imaging of adenomyosis and clinical impacts.

Adenomyosis is characterized by the presence of ectopic endometrial glands and tissue within the myometrium. The diagnosis and detection of adenomyosis on imaging have been hindered by a lack of …

Published: June 11, 2026, midnight
Thoracic Endometriosis and Catamenial Pneumothorax: Imaging Pitfalls and an Integrated Diagnostic Approach.

Catamenial pneumothorax is a rare form of recurrent spontaneous pneumothorax occurring in women in temporal association with the menstrual cycle, most commonly within 72 h before or after the onset …

Published: June 11, 2026, midnight
The effects of plasma protein levels on the risk of endometriosis: A Mendelian randomization study.

Endometriosis is a prevalent gynecologic disorder that significantly impacts women's health. However, its underlying pathogenesis remains unknown. This study aimed to ascertain causal associations between plasma protein levels and endometriosis …

Published: June 10, 2026, midnight
Interpretable machine learning for endometriosis classification: a rule-based approach.

Endometriosis is a chronic gynecological disease characterized by the growth of endometrial-like tissue outside the uterus, leading to pelvic pain, infertility, and other major health complications. Though some studies have …

Published: June 10, 2026, midnight
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