To provide health care professionals with an evidence-based approach to the diagnosis and management of endometriosis and its associated symptoms.
Endometriosis (EMs) affects approximately 10% of reproductive-age women worldwide, yet its pathogenesis remains incompletely understood. Abnormal cell differentiation and somatic mutations in the ectopic endometrial microenvironment play critical roles in …
Peritoneal inclusion cysts (PICs) are benign cystic lesions typically observed in women of reproductive age with prior pelvic surgery, endometriosis, or pelvic inflammatory disease. To date, no cases of PICs …
Formalin-fixed paraffin-embedded (FFPE) tissues represent an invaluable resource for both basic and clinical research due to their stable preservation of tissue architecture and molecular integrity. Multiplex immunofluorescence (mIF) using tyramide …
Obstructed hemivagina and ipsilateral renal anomaly syndrome was first identified by Purslow in 1922 as a result of abnormal embryologic development of the Müllerian (paramesonephric) and Wolffian (mesonephric) ducts. The …
Reproductive health unfolds across the lifespan, and individuals may move through diverse pathways - including infertility, chronic gynecologic conditions such as endometriosis, pregnancy complications, assisted reproduction or gestational carriage. These …
Endometriosis is a chronic disease that may require surgical intervention under certain circumstances. Although the condition itself is associated with impaired fertility in 30-50% of affected individuals, surgical treatment may …
Female reproductive disorders are a leading cause of infertility, affecting millions of women worldwide and resulting in significant emotional and social challenges. Despite advances in medical science, current treatment options …
Early diagnosis of ovarian cancer remains one of the most important unmet needs in gynecologic oncology because survival is strongly stage-dependent and most patients still present with disseminated disease. Conventional …
The clinical management of endometriosis encounters a significant obstacle: existing therapies inadequately address both the inhibition of ectopic lesion proliferation and the mitigation of the neuroinflammation associated with chronic pain. …