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The role of pre-operative gonadotrophin-releasing hormone agonists (GnRHa) on pain, bowel and bladder symptoms in rectovaginal/colorectal endometriosis surgery: a multicenter cohort study.

The efficacy of medical and surgical treatment of endometriosis-associated pain is a source of ongoing controversy. There is a lack of evidence about gonadotropin-releasing hormone agonists (GnRHa) use on long-term …

Published: Sept. 23, 2025, midnight
The ExPAND Study: A Prospective Association Study into Endometriosis-Associated Pain, Neurosteroid Synthesis, and TRPM3.

Endometriosis-associated pain has debilitating effects on the quality of life of patients. Despite its high prevalence in reproductive-aged women, the pathophysiology is still unknown, impeding the development of targeted treatment …

Published: Sept. 23, 2025, midnight
Interleukin 17A in the fibrotic-related processes in endometrosis in the mare.

Equine endometrosis is a chronic degenerative condition with fibrosis being one of the most significant characteristics. A growing body of evidence indicates the critical role of interleukin (IL)-17 in fibrotic …

Published: Sept. 22, 2025, midnight
Comprehensive Review of Endometriosis Based on Imaging Findings: What Radiologists Need to Know.

Endometriosis is a complex and challenging medical condition characterized by endometrial-like tissue outside the uterine cavity. MRI plays a crucial role in characterizing lesions and assessing disease. Radiologists must be …

Published: Sept. 22, 2025, midnight
Potential Changes in the Eutopic Endometrium in Endometriosis: A Narrative Review.

Endometriosis is a disease characterized by the presence of ectopic endometrium, mainly within the peritoneal cavity, and is associated with the development of inflammation due to cyclic endometrial alterations. The …

Published: Sept. 22, 2025, midnight
Dysregulation of Key Biological Processes in Endometriosis Pathophysiology.

Endometriosis is a typical disorder affecting the female reproductive system and is characterized by the presence of tissue resembling the endometrium both within and beyond the pelvic cavity. Unfortunately, the …

Published: Sept. 18, 2025, midnight
Tolerability and Shared Decision-Making in the Hormonal Management of Endometriosis-Associated Pain.

Background: The management of endometriosis-associated pain has traditionally focused on analgesic efficacy. However, with high-level evidence demonstrating therapeutic equivalence among principal hormonal classes, the paradigm has shifted towards a patient-centred …

Published: Sept. 18, 2025, midnight
Balancing Decidualization, Autophagy, and Cellular Senescence for Reproductive Success in Endometriosis Biology.

Endometriosis is a chronic disease characterized by the ectopic presence of endometrial cells that evade apoptosis and survive and proliferate under harsh environmental conditions. It is closely associated with infertility …

Published: Sept. 18, 2025, midnight
SPP1 as a key modulator of M2 macrophage polarization promotes endometriosis progression via activation of the FAK/PI3K/AKT pathway: A bioinformatics and experimental study.

Endometriosis (EMs) is a gynecological disorder characterized by chronic inflammation and an aberrant immune microenvironment. In this study, we integrated the GSE6364 dataset from the GEO database to identify differentially …

Published: Sept. 17, 2025, midnight
Leveraging the role of the microbiome in endometriosis: novel non-invasive and therapeutic approaches.

Endometriosis (EMS) is an oestrogen-dependent condition characterised by ectopic endometrial-like tissue growth with a chronic and inflammatory nature leading to severe symptoms and reduced quality of life. Emerging evidence implicates …

Published: Sept. 16, 2025, midnight
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