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Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis.

Aberrant endometrial collagen I deposition during the implantation window impairs endometrial stromal cell (ESC) decidualization, which may contribute to lower pregnancy rate in endometriosis (EMs) patients with in vitro fertilization …

Published: Nov. 23, 2024, midnight
A Case Report on Endometriosis-Associated Intestinal Tumour Following Hysterectomy: Diagnostic Challenges and Implications for Hormone Replacement Therapy (HRT) Guidelines.

Endometriosis is a complex condition that is often underdiagnosed, leaving rare but serious risks such as malignant transformation overlooked in many cases. Malignant transformation, especially in extra-gynaecological sites, poses significant …

Published: Nov. 23, 2024, midnight
Quality Improvement Report: The Sliding Sign Initiative-Facilitating Earlier Detection of Deep Endometriosis in an Academic US Department.

A delayed diagnosis of endometriosis can significantly impact a patient's quality of life. To facilitate an earlier diagnosis, we implemented a modified pelvic US protocol that included use of the …

Published: Nov. 22, 2024, midnight
Invited Commentary: Augmented Pelvic US: Path Forward to Reduce Delays in Diagnosis of Endometriosis.

Published: Nov. 22, 2024, midnight
Interventional Radiology Treatments to Address Chronic Pelvic Pain in Females.

Chronic pelvic pain (CPP) affects about one in four women globally and has a variety of etiologies, including gynecologic causes. Interventional radiology (IR) offers minimally invasive treatment options for several …

Published: Nov. 22, 2024, midnight
Percutaneous cryoablation of abdominal wall endometriosis: a systematic literature review of safety and efficacy.

To investigate over 10 years the safety and efficacy of percutaneous cryoablation for the treatment of abdominal wall endometriosis (AWE).

Published: Nov. 22, 2024, midnight
The gut-reproductive axis: Bridging microbiota balances to reproductive health and fetal development.

The gut microbiota is a highly complex microbial community residing in the digestive tract of humans and animals, closely linked to host health. Dysbiosis within the gut microbiota has been …

Published: Nov. 22, 2024, midnight
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits.

Endometriosis is a common gynecologic condition that causes chronic life-altering symptoms including pain, infertility, and elevated cancer risk. There is an urgent need for new non-hormonal targeted therapeutics to treat …

Published: Nov. 22, 2024, midnight
The causality between gut microbiota and endometriosis: a bidirectional Mendelian randomization study.

Observational studies and animal experiments had suggested a potential relationship between gut microbiota abundance and pathogenesis of endometriosis (EMs), but the relevance of this relationship remains to be clarified.

Published: Nov. 22, 2024, midnight
Identification of key genes associated with endometriosis and endometrial cancer by bioinformatics analysis.

Endometriosis (EMS) is acknowledged as a risk factor for the development of endometrial cancer (EC), although the precise molecular mechanisms that underpin this association have yet to be fully elucidated. …

Published: Nov. 22, 2024, midnight
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