Hypoxia-mediated epigenetic silencing of YTHDF2 promotes endometriosis progression via the NFE2L1-NF-κB axis.
Endometriosis (EMs) is a chronic inflammatory disease characterized by ectopic growth of endometrial-like tissues. N6-methyladenosine (m6A) modification regulates diverse cellular processes, yet its role in EMs remains unclear. Here, we …
Hormonal Dysregulation and Neuroinflammation in Endometriosis: Convergent Druggable Pathways.
Endometriosis is a chronic, estrogen-dependent disorder defined by ectopic endometrial-like tissue growth, persistent inflammation, and aberrant innervation. Emerging evidence indicates that disease progression and symptom severity are driven by a …
Dry Eye-Related Ocular Surface Assessment in a Pooled Endometriosis/Adenomyosis Cohort: A Real-World Case-Control Study.
Background/Objectives: To explore potential dry eye-related ocular surface functional alterations in women at the time of first diagnosis of endometriosis or adenomyosis in a real-world clinical setting. Methods: This was …
Endometriosis as a determinant of work disability in the Hungarian population: quantifying productivity loss and the need for workplace prevention strategies.
To quantify the impact of endometriosis on work productivity and work ability and to identify modifiable workplace targets for prevention-oriented strategies.