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Large Language Models Reveal Menstruation Experiences and Needs on Social Media.

The gender knowledge gap in medicine, particularly regarding menstruation and disorders such as endometriosis, often results in delayed diagnoses and inadequate care. Many menstruating individuals report dismissal of debilitating symptoms, …

Published: Aug. 27, 2025, 12:01 a.m.
Elucidation of the mechanism of treating endometriosis with Ge Xia-Zhu Yu decoction by means of network pharmacology and molecular docking.

This study investigates the mechanism of Ge Xia-Zhu Yu decoction (GXZYT) in the treatment of endometriosis (EMS). The active components and targets of GXZYT were screened using TCMSP database and …

Published: Aug. 27, 2025, midnight
Role of Transcription Factor, LIM Homeobox 9 (LHX9) in Inflammatory Response by PGE2 and Thrombin in SERPINA1-Silencing Endometrial Stromal Cells.

Endometriosis is hypothesized to result from retrograde menstruation where cell debris including endometrial stromal cells (ESCs) travel through the fallopian tubes. This chronic inflammatory disease is characterized by inflammatory and …

Published: Aug. 27, 2025, midnight
Reproductive Autonomy and Insurer Denials of Care: The Fine Line Between Oversight and Interference.

AbstractReproductive autonomy is a fundamental ethical principle in healthcare, yet insurance denials of care often undermine patient decision-making. This article examines a case in which a 35-year-old patient with stage …

Published: Aug. 27, 2025, midnight
Nanotechnology strategies for endometrium health: Are we on the right track?

The endometrium is a vital mucosal tissue which undergoes cyclical regeneration, differentiation, and remodeling upon hormonal, cellular, and molecular signaling networks. Dysregulation of these processes can trigger a range of …

Published: Aug. 27, 2025, midnight
Metastatic Carcinomas at the Episiotomy Site: A Systematic Literature Review.

Background/Objectives: Rarely, primary (PriCs) or metastatic (metECs) carcinomas occur in the episiotomy site. Methods: A systematic literature review of metECs was carried out. We reviewed the PRISMA guidelines and the …

Published: Aug. 27, 2025, midnight
New Perspectives on the Use of Resveratrol in the Treatment of Metabolic and Estrogen-Dependent Conditions Through Hormonal Modulation and Anti-Inflammatory Effects.

Estrogen-dependent conditions, such as endometriosis, adenomyosis, lipedema, polycystic ovary syndrome, and breast cancer, are intimately involved with hormonal changes related to estrogen and their receptors. These conditions can be expressed …

Published: Aug. 27, 2025, midnight
Six to seven times less likely to be physically active: Low self-determination and basic psychological needs support in women with endometriosis-A cluster analysis.

To explore how clusters of motivational regulations, self-determination, and basic psychological needs (BPNs) relate to physical exercise participation in women with endometriosis.

Published: Aug. 26, 2025, midnight
Correction: Disparities in Women With Endometriosis Regarding Access to Care, Diagnosis, Treatment, and Management in the United States: A Scoping Review.

[This corrects the article DOI: 10.7759/cureus.38765.].

Published: Aug. 26, 2025, midnight
High-Resolution Spatial Transcriptomics Reveals Fibroblast and Neuroimmune Microenvironments in Endometriosis Lesions.

Endometriosis is a chronic, systemic, inflammatory disease characterized by the presence of endometrium-like tissue growing outside of the uterus. One of its main symptoms is chronic pain and inflammation leading …

Published: Aug. 25, 2025, midnight
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