Infertility represents a significant global health burden, necessitating advanced therapeutic interventions. While Assisted Reproductive Technologies have revolutionized fertility treatment, they remain constrained by limited efficacy, off-target toxicity, and procedural complexity. …
Endometriosis and adenomyosis are common gynecologic disorders associated with dysmenorrhea, chronic pelvic pain, and infertility. Although they share several molecular features, the mechanisms by which endometrium-derived tissues develop distinct pathological …
Endometriosis is a chronic estrogen-dependent gynecological disorder characterized by the ectopic growth of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of women of reproductive age worldwide. It is …
Vitamin B6 is a coenzyme involved in more than 150 biochemical reactions in the body. Its intake has favorable effects for many diseases like Parkinson's disease, glaucoma, and endometriosis. Vitamin …
Ovarian endometrioma (OMA), an endometriosis subtype, involves hemorrhagic cysts formed by ectopic endometrial-like tissue, causing pelvic pain, inflammation, and infertility by disrupting ovarian function. Despite its impact, the single-cell dynamics …
Endometriosis (EMs) is a pathological condition characterized by the ectopic growth of endometrial tissue outside the uterine cavity. This study aimed to investigate the role of FOXQ1 in the pathogenesis …
This single-centre retrospective study (100 women with endometrial polyps, mean age 41.8 ± 8.2 years) investigated the association between endometrial polyps and endometriosis. Endometriosis was confirmed in 13 % of …
Endometriosis is a disease associated with pain symptoms and reduced fertility, characterized by the presence of endometrial tissue outside the uterus. SETD3 is an actin-specific histidine N-methyltransferase that regulates actin …
Endometriosis of the umbilicus is uncommon. Presenting symptoms are nonspecific and may mimic other diseases of the umbilicus, such as Sister Mary nodule, granuloma, melanoma, and umbilical hernia. Umbilical endometriosis …