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Multi-locus high-risk alleles association from interleukin's genes with female infertility and certain comorbidities.

Objective There is evidence that cytokine genes' single nucleotide polymorphisms could be the reasons behind female infertility. This study aimed to identify the role for Interleukin33 rs1048274 (G > A) …

Published: Nov. 23, 2024, midnight
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits.

Endometriosis is a common gynecologic condition that causes chronic life-altering symptoms including pain, infertility, and elevated cancer risk. There is an urgent need for new non-hormonal targeted therapeutics to treat …

Published: Nov. 22, 2024, midnight
Decreased expression of Syndecan- 1 (CD138) in the endometrium of adenomyosis patients suggests a potential pathogenetic role.

Adenomyosis is a special subtype of endometriosis, affecting the myometrium, affecting about 20% of women in the reproductive age period. Clinical symptoms and intensity are diverse and can vary from …

Published: Nov. 20, 2024, midnight
Genetic variation perspective reveals potential drug targets for subtypes of endometrial cancer - Nature.com

Genetic variation perspective reveals potential drug targets for subtypes of endometrial cancer Nature.com

Published: Nov. 15, 2024, 3:24 p.m.
[Research progress on epigenetic mechanism of reproductive disorders].

The "Developmental Origins of Health and Disease, DOHaD" theory suggests that adverse factors in early life can lead to the occurrence of chronic diseases in adulthood. In recent years, it …

Published: Nov. 14, 2024, midnight
Interrelation Between Pathoadaptability Factors and Crispr-Element Patterns in the Genomes of Escherichia coli Isolates Collected from Healthy Puerperant Women in Ural Region, Russia.

Escherichia coli is a commensal and opportunistic bacterium widely distributed around the world in different niches including intestinal of humans and animals, and its extraordinary genome plasticity led to the …

Published: Nov. 14, 2024, midnight
A Comprehensive Review of Advanced Diagnostic Techniques for Endometriosis: New Approaches to Improving Women's Well-Being.

According to the World Health Organization (WHO), endometriosis affects roughly 10% (190 million) of reproductive-age women and girls in the world (2023). The diagnostic challenge in endometriosis lies in the …

Published: Nov. 14, 2024, midnight
Cancer Genetic Risk Assessment Guidelines Expand to Meet Growing Understanding of Hereditary Risk - AAPNews Logo

Cancer Genetic Risk Assessment Guidelines Expand to Meet Growing Understanding of Hereditary Risk AAPNews Logo

Published: Nov. 7, 2024, 11:37 p.m.
Cancer genetic risk assessment guidelines expand to meet growing understanding of hereditary risk - EurekAlert

Cancer genetic risk assessment guidelines expand to meet growing understanding of hereditary risk EurekAlert

Published: Nov. 7, 2024, 3:18 p.m.
Cancer Genetic Risk Assessment Guidelines Expand to Meet Growing Understanding of Hereditary Risk - Kilgore News Herald

Cancer Genetic Risk Assessment Guidelines Expand to Meet Growing Understanding of Hereditary Risk Kilgore News Herald

Published: Nov. 7, 2024, 1:34 p.m.
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