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Association of Genetic Variations in The PIK3-AKT-mTOR Pathway with Endometriosis Susceptibility: A Preliminary Case-Control Study.

Endometriosis is a complex, heterogeneous disease with several genetic and non-genetic pathogenic factors. The phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway may influence both progression and different stages …

Published: March 11, 2025, midnight
Examining the Impact of Environmental Non-Persistent Compounds: Phthalates, BPA, and Benzophenone on Endometriosis.

Endometriosis is a debilitating condition characterized by the growth of endometrial-like tissue outside the uterus, leading to chronic pain and inflammation. While its etiology remains complex, emerging evidence implicates environmental …

Published: March 10, 2025, midnight
Bidirectional associations between endometriosis and Sjögren's syndrome in the era of multi-omics.

Published: March 10, 2025, midnight
MCP-1 promotes ILK phosphorylation at Ser246 during endometriosis development and affects the pregnancy outcome.

In women with endometriosis, monocyte chemoattractant protein 1 (MCP-1) or chemokine (C-C motif) ligand 2 (CCL2) is elevated in serum, peritoneal fluid, and endometriotic lesions, though its exact role in …

Published: March 4, 2025, midnight
Maternal autoimmune diseases and the risk of tics and Tourette's disorder in offspring: insights from Taiwan's real-world data.

Currently, tics and Tourette's disorder are burdensome neurological disorders that manifest in vocal and motor tics with onset during childhood. Previous studies have demonstrated that maternal autoimmune diseases may cause …

Published: March 4, 2025, midnight
Unveiling the connection: asthma and endometriosis - a comprehensive systematic review and meta-analysis.

Asthma and endometriosis are two prevalent chronic conditions that affect a significant portion of the population. Both conditions have been linked to inflammatory processes and immune dysregulation, suggesting the possibility …

Published: March 1, 2025, midnight
Association of urinary tract endometriosis with physical and mental health: a cross-sectional study.

Urinary tract endometriosis (UTE) is a special type of endometriosis affecting the urinary system, yet the physical and mental health of UTE patients remain unexplored.

Published: Feb. 28, 2025, midnight
A systematic review and meta-analysis of advanced oxidative protein products levels (AOPP) levels in endometriosis: association with disease stage and clinical implications.

Endometriosis is a common cause of chronic pelvic pain and lacks precise pathophysiological mechanisms. Advanced oxidation protein products (AOPPs), markers of oxidative stress and inflammation, are implicated in pain-related diseases …

Published: Feb. 28, 2025, midnight
Endometriosis as a risk factor for ischemic and hemorrhagic stroke: a population-based cohort study.

We completed a retrospective population-based cohort study using administrative data from Ontario females from 1993-2015 to examine the association between a diagnosis of endometriosis and stroke. We identified 166 853 …

Published: Feb. 28, 2025, midnight
Role of soluble neural cell adhesion molecule, soluble IL-2 receptor ɑ, and IL-2 in pelvic pain severity and their association with endometriosis in infertile women.

Pelvic pain, often associated with endometriosis, significantly affects women's quality of life. This study explored the soluble neural cell adhesion molecules (sNCAM), soluble interleukin 2 receptor α (sIL-2Rα), and IL-2 …

Published: Feb. 27, 2025, midnight
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