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Polychlorinated Biphenyls Alter Estrogen Receptor beta-Mediated Epigenetic Regulation, Promoting Endometriosis.

Endometriosis is a pathological condition characterized by the ectopic growth of endometrial cells, leading to chronic pelvic pain and infertility. Epidemiological studies have associated exposure to dioxin-like polychlorinated biphenyls (PCBs), …

Published: Oct. 7, 2025, midnight
Impact of endocrine disruptors on female fertility: an update.

Endocrine disruptors (EDs) are a heterogeneous group of natural or synthetic chemicals capable of interfering with hormonal regulation. Widely present in plastics, cosmetics, pesticides, food packaging, and household products, they …

Published: Oct. 7, 2025, midnight
Circulating microRNAs and Endometriosis: A Comprehensive Analysis and Validation of Identified Biomarkers in the Indian Population.

Endometriosis is a prevalent condition where tissue similar to the uterine lining grows outside the uterus, causing pain and infertility. Diagnosing endometriosis typically requires invasive procedures like laparoscopy. MicroRNAs (miRNAs) …

Published: Oct. 1, 2025, midnight
Evaluating the diagnostic potential of CA-125 and miRNA levels in endometriosis: A narrative review.

Endometriosis, a common and complex gynecologic disorder, continues to pose a challenge to clinicians in diagnosis process due to its complexity. The aim of this review was to examine cancer …

Published: Oct. 1, 2025, midnight
Analysis of diagnostic apoptosis-related biomarkers and immune cell infiltration characteristics in endometriosis by integrating bioinformatics and machine learning.

Endometriosis (EMs) is a chronic disease affecting millions of women worldwide, yet its pathogenesis remains unclear, and current diagnostic methods are limited. This study based on the EMs dataset from …

Published: Sept. 29, 2025, midnight
Shared and distinct molecular pathways in eutopic endometrium of endometriosis and adenomyosis patients: a transcriptomic study in Chinese women.

Endometriosis (EMs) and adenomyosis (AD) are prevalent gynecological disorders with overlapping symptoms but potentially distinct pathophysiology. This study was to understand different gene expression patterns of eutopic endometrium between EMs …

Published: Sept. 26, 2025, midnight
Endometriosis-associated infertility alters the microRNA signatures of cumulus cells with a particularly pronounced effect in oocytes that failed fertilization.

Endometriosis (E) is multifactorial disease affecting around 10% of women worldwide. The association between E and infertility is clinically well recognized. For E patients to achieve a successful pregnancy, assisted …

Published: Sept. 26, 2025, midnight
Decreased Glycolysis due to LDHA m6A methylation in Endometrium of endometriosis impairs its decidualization and contributes to related infertility.

Endometriosis-related infertility is a prevalent reproductive health concern of global significance. Functional abnormalities of the endometrium are increasingly recognized as a pivotal contributor to infertility in affected individuals. In the …

Published: Sept. 26, 2025, midnight
miRNA expression haplotype in Hispanics with endometriosis.

Endometriosis affects approximately 10% of women of reproductive age; this prevalence may be underestimated, mostly in developing countries, including Mexican and Hispanic populations, due to socioeconomic barriers and limited access …

Published: Sept. 25, 2025, midnight
NAC1 Regulates PCK2 Expression and Activates Truncated Gluconeogenesis for Growth Advantage in Ovarian Cancer Cells.

Nucleus accumbens-associated protein 1 (NAC1), a cancer-related transcriptional regulator, is overexpressed in several malignancies, including ovarian cancer. However, its role in ovarian carcinogenesis remains unclear. We aimed to investigate whether …

Published: Sept. 25, 2025, midnight
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