Defects in the DNA Damage Response of Patient-derived Endometriosis Stromal Cells.
With each menstrual cycle, endometrial cells rapidly proliferate and decidualize in preparation for pregnancy. Such rapid proliferation generates replication stress and results in DNA damage with irreparable cells undergoing senescence. …
Decoding uterine contractility: from physiology to pathology, through emerging technologies.
Uterine contractility has emerged as a potential key element in the orchestration of female reproductive functions, with specific motility patterns seemingly aligning with hormonal fluctuations throughout the menstrual cycle. These …
Rosalind Franklin University Leader in Reproductive Immunology to Speak at the 2025 American Society of Reproductive Medicine Congress - The Malaysian Reserve
Rosalind Franklin University Leader in Reproductive Immunology to Speak at the 2025 American Society of Reproductive Medicine Congress The Malaysian Reserve
Reframing Endometriosis: Interplay of NETs, Macrophages, and Lymphocytes at the Crossroads of Disease Progression, Infertility, and Malignant Transformation.
Endometriosis (ENDO) is a painful, chronic gynecological disease widely affecting women globally. While traditionally classified as a hormonal disorder, ENDO is now increasingly recognized as a multifaceted immune-mediated syndrome driven …