Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by ectopic endometrial-like glands and stroma, persistent pelvic inflammation, pain, infertility, and frequent recurrence. The limited availability of nonhormonal and lesion-directed therapies …
Endometriomas are a common manifestation of endometriosis and can present as unilateral or bilateral disease. While bilateral involvement is clinically suspected to reflect more severe disease and greater impairment of …
Endometriosis is a heterogeneous gynecological disorder for which experimental model development is often limited by diagnostic ambiguity and the restricted lifespan of primary epithelial cultures. Although immortalization strategies enable long-term …
Thoracic endometriosis is a rare manifestation of extra pelvic endometriosis and it is often missed because of its variable clinical presentation. A 33-year-old woman undergoing evaluation for secondary subfertility presented …
To compare obstetric and neonatal outcomes between women with surgically confirmed deep infiltrating endometriosis (DIE) and superficial endometriosis, focusing on lesion-specific risk profiles. This retrospective cohort study included women with …
Endometriosis is a chronic inflammatory condition affecting 10% of reproductive-age women. Current treatments remain limited and non-curative. While its biology is largely informed by human biospecimens, sample heterogeneity and methodological …
The objective of this study is to evaluate the effects of bromelain on serum endocannabinoid levels and oxidative stress markers in a rat model of surgically induced endometriosis.
Earlier examinations of how risk factors relate to endometriosis (EMT) have largely depended on observational designs, which arrived at conflicting conclusions. The present approach seeks to probe the causal association …
The meiotic spindle is essential for accurate chromosome segregation during oocyte maturation and fertilization, and its alteration might be considered a major contributor to age-related aneuploidy and reproductive failure. Spindle …
Objectives. The aim of the study was to develop a diagnostic method for estrogen hypersensitivity syndrome in proliferative benign diseases of the female reproductive system. Using the example of endometriosis, …