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Re-Analysis of Public Transcriptomes Identifies a Candidate Histone-Cluster Signal in Eutopic Endometrium: A Hypothesis-Generating Link to Chronic Pelvic Pain.

Endometriosis is a leading cause of chronic pelvic pain (CPP), but the public transcriptomic datasets analysed here contain no pain phenotype, links to CPP are therefore hypothesis-generating.

Published: Sept. 19, 2026, midnight
Risk factors for intraoperative adhesion in ovarian endometriosis patients: A retrospective study.

Endometriosis is a common gynecological disease that can cause pelvic adhesions. Severe adhesions increase the difficulty of surgery, resulting in prolonged operation time, increased intraoperative bleeding, and increased complications such …

Published: Sept. 16, 2026, midnight
Aetiology of pelvic neuropathies in women: a narrative review.

Pelvic neuropathy is an under-recognised contributor to chronic pelvic pain in women, yet a structured overview of its identifiable causes has been lacking. In this narrative review we searched PubMed, …

Published: Sept. 16, 2026, midnight
Liriodendrin alleviates endometriosis via PPARγ activation and inhibition of NLRP3 inflammasome-mediated pyroptosis.

Excessive activation of inflammatory responses and oxidative stress plays a critical role in the pathophysiology of endometriosis (EMs), which is characterized by ectopic lesion growth and chronic pelvic pain. However, …

Published: Sept. 16, 2026, midnight
The microbiome-inflammasome axis in endometriosis-associated chronic pelvic pain: mechanisms and therapeutic opportunities from an immunological perspective.

Endometriosis (EMs) is increasingly recognized as a chronic inflammatory disease in which innate immune dysregulation plays an important role. Its immunopathological features include macrophage polarization imbalance, with M1-skewed activation in …

Published: Sept. 16, 2026, midnight
Chronic abdominal pain and dyspareunia in endometriosis: pain therapy with a nerve and muscle stimulation device with biofeedback function.

Endometriosis (EM) is frequently associated with chronic pelvic pain (CPP) and dyspareunia, often linked to secondary pelvic floor dysfunction and hypertonicity. To evaluate whether the use of an intravaginal electromyography …

Published: Sept. 15, 2026, midnight
The Endocannabinoid System in Endometriosis-Associated Pain: Mechanisms, Molecular Targets, and Therapeutic Implications.

Endometriosis is a chronic gynecological disorder affecting approximately 10% of reproductive-age women, characterized by the ectopic growth of endometrial tissue and severe pain, including dysmenorrhea, chronic pelvic pain, dyspareunia, dysuria, …

Published: Sept. 15, 2026, midnight
Transperineal Ultrasound in Chronic Pelvic Pain: A Systematic Review.

This systematic review aimed to explore the application and effectiveness of transperineal ultrasound as a diagnostic tool for evaluating pelvic floor musculature (PFM) dysfunction in patients with chronic pelvic pain …

Published: Sept. 14, 2026, midnight
Non-invasive brain stimulation in chronic pelvic pain: a systematic review.

Chronic pelvic pain (CPP) is increasingly recognized as a disorder of altered central pain processing, providing a strong rationale for non-invasive brain stimulation (NIBS) as a therapeutic approach. However, use …

Published: Sept. 10, 2026, midnight
Immune-nutritional interactions in endometriosis: current evidence and future perspectives in disease management.

Endometriosis is a chronic estrogen-dependent inflammatory disorder affecting approximately 10% of women of reproductive age. It remains a major contributor to chronic pelvic pain, infertility, and reduced quality of life. …

Published: Sept. 7, 2026, midnight
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