Endometriosis affects one in seven women in Australia and is a significant public health concern. Access to appropriate health information is essential for informed decision-making and quality of life, especially …
Exosomes are nanoscale extracellular vesicles that mediate intercellular communication by transporting microRNAs, proteins, and lipids. Generated through Endosomal Sorting Complex Required for Transport (ESCRT)-dependent mechanisms or ESCRT-independent pathways, exosomes are …
The human microbiome, particularly the gut and reproductive tract microbiota, plays a critical role in regulating fertility through complex molecular and immunological mechanisms. This review synthesizes emerging evidence on the …
Endometriosis is a chronic condition where tissue resembling the uterine lining grows elsewhere in the pelvis, often causing pain, infertility, and inflammation. For decades, textbooks and research papers have described …
Patients with endometriosis are at a high risk of developing pelvic inflammatory disease. This case series presents three cases of colo-ovarian fistulas associated with endometriosis, highlighting the potential for conservative …
Endometriosis is a painful gynecological inflammatory disease affecting up to 10% of females. When released by sensory neurons, calcitonin gene-related peptide (CGRP) shapes immunity, a process known as neuroimmune communication. …
Studies have shown that the iron concentration in the peritoneal fluid of women is associated with the severity of endometriosis. Therefore, investigation of iron metabolism-related genes (IM-RGs) in endometriosis holds …
Female infertility and reproductive disorders represent a significant global health challenge, with complex etiologies often linked to impaired cellular communication, inflammation, and tissue dysfunction. Exosomes (EXOs), nanosized extracellular vesicles laden …
Regulated cell death (RCD) is a fundamental biological process essential for tissue homeostasis and disease regulation. Increasing evidence has demonstrated that RCD plays a pivotal role in the pathogenesis of …
Lipidomics, an emerging field in medical research, has deepened our understanding of lipid metabolism, signal transduction pathways, and intercellular communication through qualitative and quantitative analyses of patient lipid profiles. It …