Interleukin 37 (IL‑37), a member of the IL‑1 family, is recognized as an anti‑inflammatory cytokine. The anti‑inflammatory properties of recombinant human (rh)IL‑37 have been confirmed in vitro and its protective …
While having a chronic medical disease (CMD) increases use of analgesics and anti-inflammatory drugs, sufficient knowledge regarding patterns of use during pregnancy is lacking. We aimed to describe ibuprofen use …
Endometriosis is a benign yet debilitating condition, and its molecular complexity remains unexplored. Although clinically recognized, its genetic landscape has long been overlooked. This review analyses cancer-associated mutations (CAMs) identified …
To investigate associations between current use of menopausal hormone therapy and development of venous thromboembolism, ischaemic stroke, and myocardial infarction.
Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by ectopic endometrial-like glands and stroma, persistent pelvic inflammation, pain, infertility, and frequent recurrence. The limited availability of nonhormonal and lesion-directed therapies …
Endometriomas are a common manifestation of endometriosis and can present as unilateral or bilateral disease. While bilateral involvement is clinically suspected to reflect more severe disease and greater impairment of …
Endometriosis is a heterogeneous gynecological disorder for which experimental model development is often limited by diagnostic ambiguity and the restricted lifespan of primary epithelial cultures. Although immortalization strategies enable long-term …
Endometriosis (EM) is a severe chronic inflammatory disease characterized by the presence of endometrium-like tissue outside the uterine cavity, causing pain and significantly reducing quality of life. Worldwide, around 10% …
Endometriosis is a chronic inflammatory condition affecting 10% of reproductive-age women. Current treatments remain limited and non-curative. While its biology is largely informed by human biospecimens, sample heterogeneity and methodological …
Endometriosis is a chronic inflammatory disease characterized by substantial heterogeneity in pain, lesion behavior, and treatment response. Although hormonal and surgical therapies can reduce disease activity and symptoms, their effects …