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The Microbiota-Endometriosis Axis: An Immune-Endocrine Integration Model and Emerging Therapeutic Targets.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by the ectopic implantation and persistence of endometrial-like tissue outside the uterine cavity. Despite its high prevalence and significant impact on quality …

Published: May 28, 2026, midnight
From gut-reproductive microbiota to ferroptosis: a comprehensive insight into the molecular-pathogenicity of endometriosis.

Endometriosis (EMS) is a highly heterogeneous chronic gynecological disease characterized by pain, infertility, and relapse, with its etiology and pathogenesis not yet fully elucidated. Traditional theories, including "retrograde menstruation," "implantation …

Published: May 22, 2026, midnight
Unveiling the Bidirectional Relationship on the Effect of Gut Microbiota and Female Infertility: A Narrative Review.

Dysbiosis is the substitution of the normal gut flora with a dysfunctional array of organisms that influences the outcome of multiple inflammatory pathways, contributing to systemic inflammation and various disease …

Published: May 6, 2026, midnight
The Gut-Reproduction-Oral-Immune Axis: Microbial Dysbiosis as a Shared Driver in Polycystic Ovary Syndrome and Endometriosis.

Published: April 18, 2026, midnight
The role of gut microbiota in modulating estrogen in the inflammatory milieu of endometriosis: A molecular and pathophysiological perspective.

Endometriosis is a prevalent estrogen-dependent chronic inflammatory condition that affects millions of women of reproductive age worldwide. It is characterized by the growth of endometrial tissue outside the uterine cavity, …

Published: Feb. 24, 2026, midnight
A Dive into the Invisible: The Vaginal and Endometrial Microbiota in Gynecologic and Obstetric Disorders: A Narrative Review.

The human microbiota is increasingly recognized as a key component of women's reproductive health. This narrative review examines the vaginal, endometrial, and gut microbiota and their roles in the pathogenesis …

Published: Feb. 17, 2026, midnight
Molecular mechanisms in endometriosis: linking JAK/STAT pathway, ferroptosis, and microbial dysbiosis.

Endometriosis is a chronic gynaecological disorder characterized by ectopic endometrial growth, inflammation, pain, and infertility. Current therapies, largely hormonal and surgical, have limited efficacy and compromise fertility, underscoring the need …

Published: Feb. 14, 2026, midnight
Impact of hormonal treatments for endometriosis on the reproductive microbiome: a systematic review.

The reproductive microbiome plays a key role in disease progression and fertility in women with endometriosis. Vaginal and endometrial dysbiosis has been increasingly linked to inflammation, impaired reproductive outcomes, and …

Published: Feb. 12, 2026, midnight
Gut Microbiota Alterations and Reproductive Tract Dysbiosis in Endometriosis: A Systematic Review.

Background and Objectives: Endometriosis is a chronic, estrogen-dependent inflammatory disease with multifactorial pathogenesis. Increasing evidence suggests that alterations in the gut and reproductive tract microbiota may contribute to disease development, …

Published: Feb. 10, 2026, midnight
Advances in the Role of Endometrial Microbiota Alterations in the Pathogenesis of Endometriosis.

The uterine cavity was formerly considered sterile; however, over recent years, researchers have identified the presence of endometrial microbiota. An imbalance in the endometrial microbiota, or dysbiosis, has been shown …

Published: Feb. 9, 2026, midnight
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