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Integrative Transcriptomic Analysis Identifies a Key Candidate Gene Bridging Inflammation and DNA Repair in Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by the ectopic implantation of endometrial-like tissue. Although retrograde menstruation is highly prevalent, only a subset of women develops the disease. This …

Published: July 21, 2026, midnight
Patient-tailored symptom tracking in endometriosis: a framework to explore disease variability and burden.

Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by highly individualized, multisystemic symptoms, affecting approximately 10% of females. In this work, we present a long-term prospective study in which 34 …

Published: July 17, 2026, midnight
Adjunctive vitamin D supplementation in women receiving dienogest therapy for endometriosis: a randomized controlled trial.

Endometriosis is a chronic, estrogen-dependent inflammatory disease that causes debilitating pain and significantly impairs quality of life. Due to its anti-inflammatory and immunomodulatory properties, vitamin D has been proposed as …

Published: July 16, 2026, midnight
N-Acetylcysteine in Endometriosis: A Systematic Review of Biological Rationale and Clinical Evidence.

Endometriosis is a chronic inflammatory and estrogen-dependent disease in which oxidative stress, immune dysregulation, and lesion-supportive microenvironmental signaling contribute to lesion development. N-acetylcysteine (NAC), a glutathione-replenishing and redox-modulating agent, has …

Published: July 16, 2026, midnight
Benign Metastasizing Leiomyoma With Myomatous Erythrocytosis Syndrome: First Reported Coexistence as a Unified Hormonal Syndrome.

Benign metastasizing leiomyoma (BML) is a rare condition characterized by histologically benign smooth muscle tumours arising at extrauterine sites, most commonly the lungs, in women with a history of uterine …

Published: July 15, 2026, midnight
Bisphenol exposure and gynecological health: A narrative review of current evidence and knowledge gaps.

The widespread use of plastic has led to exposure to chemicals like bisphenols (BPs), particularly bisphenol A (BPA), which are crucial in the production of polycarbonate plastics and epoxy resins. …

Published: July 13, 2026, midnight
Comprehensive transcript and protein profiling reveals ERα rather than ERβ as the predominant estrogen receptor in human endometriotic lesions.

Endometriosis (EMS) is a chronic estrogen-dependent inflammatory disease. Although several studies have suggested a key role for estrogen receptor ERβ in EMS lesion development, its detection has been challenged by …

Published: July 11, 2026, midnight
GnRH Analogues for the Treatment of Endometriosis-Related Pain: A Narrative Review.

Endometriosis is a chronic estrogen-dependent condition affecting women of reproductive age and commonly presents with dysmenorrhea, chronic pelvic pain, dyspareunia, and infertility. In a substantial proportion of patients, pain persists …

Published: July 11, 2026, midnight
Immune escape in endometriosis: mechanisms, reprogramming strategies, and precision interventions.

Endometriosis is a prevalent estrogen-dependent inflammatory disorder that compromises women's quality of life and fertility through chronic pelvic pain, inflammation, and reproductive dysfunction. Current clinical management remains largely palliative, with …

Published: July 10, 2026, midnight
Metabolic remodeling of endometriosis microenvironment: Energy stress and immune evasion.

Endometriosis (EMs) is an estrogen-dependent chronic inflammatory gynecological disease characterized by ectopic growth of endometrial tissues, leading to dysmenorrhea, pelvic pain, and infertility. Although the retrograde menstruation theory clarifies the …

Published: July 9, 2026, midnight
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