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Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach.

Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, …

Published: Feb. 13, 2026, midnight
From Pelvis to Groin: Non-Communicating Rudimentary Uterine Horn and Endometriosis Presenting as an Inguinal Hernia in a Woman with a Solitary Pelvic Kidney.

Müllerian anomalies complicated by extrapelvic endometriosis are uncommon, and herniation of Müllerian remnants into the inguinal canal is exceptionally rare. These complex presentations pose significant diagnostic challenges arising from intricate …

Published: Feb. 11, 2026, midnight
Reply of the Authors: Safety and pharmacology of AMY109, a long-acting anti-interleukin-8 antibody, for endometriosis: a double-blind, randomized phase 1 trial.

Published: Feb. 10, 2026, midnight
Comments on "Safety and pharmacology of AMY109, a long-acting anti-interleukin-8 antibody, for endometriosis: a double-blind, randomized phase 1 trial".

Published: Feb. 10, 2026, midnight
Efficacy and Safety of Traditional Chinese Medicine Retention Enema for Endometriosis: A Systematic Review and Meta-Analysis.

Background/Objectives: Herbal retention enema is widely used in Traditional Chinese Medicine for the management of endometriosis; however, its clinical efficacy and safety have not been systematically evaluated. Methods: Ten electronic …

Published: Feb. 6, 2026, midnight
Safety, Pharmacokinetics, and Sex Hormone Suppression of LY01021 versus Relugolix: A Single- and Multiple-Dose Escalation Study.

LY01021 is a novel oral small-molecule gonadotropin-releasing hormone (GnRH) receptor antagonist intended for the treatment of various sex hormone-dependent disorders. This study aimed to evaluate the safety, tolerability, pharmacokinetics (PK), …

Published: Feb. 5, 2026, midnight
Safety and efficacy of hormonal therapies used to treat endometriosis in women suffering migraine.

Hormonal therapy is the cornerstone of long-term endometriosis management, especially for women deferring surgery. In patients with comorbid migraine - a common, disabling condition - therapeutic choices must balance efficacy …

Published: Feb. 2, 2026, midnight
Innervation of the Uterus: An Anatomical Study With Application to Better Understanding Pelvic Pain in Women.

Pelvic pain has a significant impact on quality of life, especially when associated with benign pelvic diseases, such as endometriosis or chronic conditions leading to persistent discomfort. A substantial proportion …

Published: Feb. 1, 2026, midnight
Assisted Reproductive Technology in Women with Endometriosis and a History of Catamenial Pneumothorax: Reproductive Outcomes and Safety Considerations.

To describe reproductive outcomes and clinical safety considerations associated with assisted reproductive technology (ART) in women with a history of surgically treated catamenial pneumothorax (thoracic endometriosis syndrome).

Published: Feb. 1, 2026, midnight
[Efficacy and safety of triptorelin acetate microspheres for injection versus triptorelin acetate for injection in Chinese patients with endometriosis: a multicenter, randomized, double-blind, phase Ⅲ non-inferiority clinical trial].

Objective: To evaluate the efficacy and safety of triptorelin acetate microspheres for injection compared with triptorelin acetate for injection in the treatment of endometriosis. Methods: A total of 392 patients …

Published: Jan. 31, 2026, midnight
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