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Bidirectional Mendelian randomization and cross-sectional study reveal depression as a causal risk factor for endometriosis.

Endometriosis (EMs) and depression are both common conditions that have a significant negative impact on quality of life. However, it is still unclear about the relationship between them. The study …

Published: Nov. 21, 2025, midnight
Endometriosis - on the intersection of modern environmental pollutants and ancient genetic regulatory variants - Nature

Endometriosis - on the intersection of modern environmental pollutants and ancient genetic regulatory variants Nature

Published: Nov. 20, 2025, 5:11 p.m.
Establishment and Characterization of a New Immortalized Human Adenomyosis Epithelial-Like Cell Line, tAEC21†.

Adenomyosis occurs when endometrial glands and stroma grow within the uterine myometrium. As a clinically significant disease, adenomyosis causes substantial pelvic pain and heavy menstrual bleeding. It remains understudied due …

Published: Nov. 20, 2025, midnight
Endometriosis - on the intersection of modern environmental pollutants and ancient genetic regulatory variants.

Endometriosis is a chronic, estrogen-driven inflammatory disorder affecting approximately 10% of reproductive-aged women globally. Despite increasing genomic insights into advanced-stage disease, the genetic underpinnings of early-stage endometriosis remain poorly understood, …

Published: Nov. 20, 2025, midnight
Proteome-wide Mendelian randomization identifies β-nerve growth factor as a target for endometriosis.

Endometriosis is a chronic inflammatory disorder with poorly understood mechanisms. Inflammatory proteins are hypothesized to play a causal role, but evidence remains limited. We performed a 2-sample Mendelian randomization study …

Published: Nov. 16, 2025, midnight
The Evolution of In Vitro Fertilization Practices in Saudi Arabia: Historical Perspectives and Future Directions.

In vitro fertilization (IVF) has revolutionized assisted reproductive technologies (ART), profoundly transforming infertility treatment since its inception. This procedure involves fertilizing an egg with sperm in a controlled laboratory environment, …

Published: Nov. 16, 2025, midnight
Causal associations between sleep disorders and endometriosis: A Mendelian randomization analysis.

Evidence have indicated a correlation between sleep disorders and endometriosis, but the causal relationship remains uncertain. This study utilized Mendelian randomization (MR) approach to investigate the causal associations between sleep …

Published: Nov. 10, 2025, midnight
Monogenic Contributions to Familial Endometriosis: A Scoping Review.

Endometriosis is a chronic gynecological disorder characterized by the ectopic growth of endometrial-like tissue, with emerging evidence highlighting a significant genetic contribution to its etiology. While genome-wide association studies have …

Published: Nov. 7, 2025, midnight
Genetic variation associated with side effects of hormonal contraception exposure: A narrative review - Frontiers

Genetic variation associated with side effects of hormonal contraception exposure: A narrative review Frontiers

Published: Oct. 30, 2025, 5:03 p.m.
COMMENTARY: Early cancer detection, with new tools and genetic testing, saves lives - Jefferson City News Tribune

COMMENTARY: Early cancer detection, with new tools and genetic testing, saves lives Jefferson City News Tribune

Published: Oct. 30, 2025, 9 a.m.
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