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Effects of Mono- (2-ethylhexyl) phthalate and Phthalic Acid Monobenzyl Ester on endometriosis using network toxicology, machine learning and molecular docking techniques.

Phthalate metabolites Mono- (2-ethylhexyl) phthalate(MEHP) and Phthalic Acid Monobenzyl Ester (MBZP) are widely present in the environment, can interfere with the endocrine system and accumulate in human tissues, and are …

Published: Aug. 8, 2025, midnight
Optimizing endometriosis diagnosis and mapping: The important role of advanced transvaginal ultrasound.

Endometriosis is estimated to affect 5%-10% of women of reproductive age, making timely diagnosis essential for initiating treatment, alleviating symptoms, and reducing the risk of disease progression. Unfortunately, the diagnostic …

Published: July 29, 2025, midnight
Diagnostic Accuracy of Transvaginal Ultrasonography for Endometriosis According to the International Deep Endometriosis Analysis Consensus.

To evaluate the diagnostic accuracy of transvaginal ultrasonography (TVUS) in detecting deep endometriosis, ovarian endometriosis, and superficial endometriosis using the IDEA (International Deep Endometriosis Analysis) consensus and novel International Terminology …

Published: Feb. 20, 2025, midnight
Pharmacovigilance study of the association between progestogen and depression based on the FDA adverse event reporting System (FAERS).

Progestogens commonly used in the clinic include levonorgestrel, etonogestrel, medroxyprogesterone, hydroxyprogesterone, progesterone, desogestrel, and megestrol. Progestogens are widely used for contraception and the treatment of endometriosis, threatened abortion and other …

Published: Jan. 8, 2025, midnight
GnRH Peptide Antagonist: Comparative Analysis of Chemistry and Formulation with Implications for Clinical Safety and Efficacy.

Overexpression of the gonadotropin-releasing hormone receptor (GnRH-R) plays a vital role in the advancement of reproductive malignancies such as ovarian, endometrial, and prostate cancer. Peptidomimetic GnRH antagonists are a substantial …

Published: Dec. 31, 2024, midnight
Recent Trends in Medical Management of Endometriosis.

Endometriosis affects about 10 percent women in the reproductive age group globally and approximately 42 million in India. Managing the patient's pain symptoms associated with endometriosis appears to be the …

Published: Dec. 26, 2024, midnight
AURKA inhibits the decidualization of the eutopic endometrium in endometriosis through NF-κB p65†.

Endometriosis is an estrogen dependent disease, which is related to infertility. Decidualization is a prerequisite for successful implantation of human embryos, and endometriosis affects the occurrence of decidualization. However, the …

Published: Dec. 3, 2024, midnight
[Psychoemotional state and sexual function in women with chronic pelvic pain in genital endometriosis].

The purpose of this review is to consider current ideas about psychophysiology of chronic pelvic pain (CPP) in external genital endometriosis (GE), as well as the impact of the psychoemotional …

Published: Nov. 23, 2024, midnight
Elective uterine preservation: a novel concept to tackle reproductive ageing. Fertility preservation beyond ovaries.

With a growing number of women in developed countries having children later in life, it is time to rethink women's reproductive health. This trend of 'delayed parenthood' reflects a complex …

Published: Nov. 10, 2024, midnight
Menstruation: An Important Indicator for Assessing Stroke Risk and Its Outcomes.

In recent years, stroke incidence in older adults has declined strikingly, but stroke in younger women has become more common. Abnormalities of menstruation, the shedding of the uterine lining at …

Published: Nov. 7, 2024, midnight
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