Biomarkers and Immunotherapy in Endometrial Cancer: Mechanisms and Clinical Applications Frontiers
The female reproductive system (FRS) exhibits unique immunological characteristics, balancing defense against pathogens with tolerance to sperm and semi-allogeneic embryos. Key players include decidual natural killer (dNK) cells, immune checkpoint …
Endometriosis (EMs) is a chronic inflammatory disorder characterized by dysregulated innate immunity, particularly impaired cytotoxic function of natural killer (NK) cells. As pivotal effectors of the innate immune response, NK …
Endometriosis (EMS) is a persistent, inflammatory condition that relies on estrogen and is distinguished by the proliferation of endometrial tissue outside the confines of the uterus. The impact on the …
GSK expands cancer treatment options in India with launch of immunotherapy and PARP inhibitor connectedtoindia.com
Immunotherapy for High-Grade Endometrial Stromal Sarcoma: A Narrative Review Bridging Molecular Insights to Clinical Translation Frontiers
Through a combination of single-cell/single-nucleus RNA-sequencing (sc/snRNA-seq) data analysis, immunohistochemistry, and primary macrophage studies, we have identified pathogenic macrophages characterized by TET3 overexpression (Toe-Macs) in three major human diseases associated …
Immunotherapy plus chemotherapy approved for endometrial cancer The Pharmaceutical Journal
Breakthrough treatment combines immunotherapy and chemotherapy National Health Executive
NICE approves first immunotherapy combination for endometrial cancer Wired Gov