GPR30 (G-protein coupled receptor 30) plays a key role in regulating reproductive processes, particularly through estrogen signaling. Previous studies have linked GPR30 polymorphisms to female reproductive disorders such as infertility, …
Oocyte quality is the primary determinant of success in assisted reproductive technologies (ART), and mitochondrial dysfunction is increasingly recognized as a central mediator of poor oocyte competence across advanced maternal …
Endometriosis affects approximately 10% of women of reproductive age and is associated with infertility in up to half of those diagnosed. Despite decades of research, the molecular basis of its …
Endometriosis, affecting 10-15% of women of reproductive age, is more commonly found on the left side of the pelvis. This laterality phenomenon's etiology remains obscure. We reviewed the existing literature …
Endometriosis is an estrogen-dependent inflammatory disorder associated with pelvic pain, infertility, repeated treatment, and impaired quality of life. Thyroid dysfunction and thyroid autoimmunity are also common in reproductive-aged women and …
EMs is a chronic, estrogen-dependent systemic inflammatory disorder defined by the ectopic implantation of endometrial glands and stroma and is frequently associated with dysmenorrhea, chronic pelvic pain, infertility, and substantial …
Endometriosis is a common gynecological disorder characterized by the growth of endometrial-like tissue outside the uterine cavity, leading to chronic inflammation, pelvic pain, and infertility. Reliable mouse models are essential …
Endometriosis-Associated Implantation Failure: Pathophysiology, Biomarkers, and Emerging Therapeutic Strategies Cureus
Implantation failure remains a major challenge in assisted reproductive technology (ART) and is a significant contributor to infertility in women with endometriosis. Beyond mechanical distortion and ovarian dysfunction, increasing evidence …
Emerging evidence suggests microbial dysbiosis may contribute to gynaecological pathologies, including endometriosis and recurrent implantation failure (RIF). The vaginal microbiome is well-characterised, with Lactobacillus-dominance as a hallmark of health, yet …