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Selective progesterone receptor modulators for the treatment of dysmenorrhea: an update.

Dysmenorrhea is a painful symptom associated with uterine contractions and menstrual bleeding and is treated by administering analgesic drugs. Since progesterone receptors (PRs) have a major role in regulating uterine …

Published: Jan. 14, 2025, midnight
Robert Irwin Reacts to Being Labeled a Heartthrob by Fans in Thirsty Comments (Exclusive) - AOL

Robert Irwin Reacts to Being Labeled a Heartthrob by Fans in Thirsty Comments (Exclusive) AOL

Published: Jan. 5, 2025, 7:22 a.m.
Human-AI collaborative multi-modal multi-rater learning for endometriosis diagnosis.

Endometriosis, affecting about 10% of individuals assigned female at birth, is challenging to diagnose and manage. Diagnosis typically involves the identification of various signs of the disease using either laparoscopic …

Published: Dec. 2, 2024, midnight
Linaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscerovisceral cross-talk.

Endometriosis, an estrogen-dependent chronic inflammatory disease, is the most common cause of chronic pelvic pain. Here, we investigated the effects of linaclotide, a Food and Drug Administration-approved treatment for IBS-C, …

Published: Oct. 14, 2024, 1:22 p.m.
Impact of Estetrol Combined with Drospirenone on Blood Coagulation and Fibrinolysis in Patients with Endometriosis: A Multicenter, Randomized, Open-Label, Active-Controlled, Parallel-Group Study.

Venous thromboembolism is a serious safety concern in women using combined oral contraceptives; ethinyl estradiol (EE) is widely used as an estrogen. Estetrol (E4) is a native estrogen with selective …

Published: Oct. 13, 2024, 4:35 p.m.
M1 macrophages as promising agents for cell therapy of endometriosis.

Endometriosis is a chronic estrogen-dependent disease characterized by the presence of endometrial glands and stroma outside their normal anatomical location. While laparoscopic removal of foci remains the gold standard therapy, …

Published: Aug. 14, 2024, midnight
Levonorgestrel intrauterine system versus dienogest effect on quality of life of women with deep endometriosis: a randomized open-label clinical trial.

Women with deep infiltrating endometriosis (DIE) can benefit from the use of progestins. Our aim is to explore if levonorgestrel-releasing intrauterine system (LNG-IUS) non inferior to dienogest (DNG) in improving …

Published: Aug. 7, 2024, midnight
FDA Expands Durvalumab Label to Endometrial Cancer - Medscape

FDA Expands Durvalumab Label to Endometrial Cancer Medscape

Published: June 17, 2024, 7 a.m.
Long acting progestogens versus combined oral contraceptive pill for preventing recurrence of endometriosis related pain: the PRE-EMPT pragmatic, parallel group, open label, randomised controlled trial - The BMJ

Long acting progestogens versus combined oral contraceptive pill for preventing recurrence of endometriosis related pain: the PRE-EMPT pragmatic, parallel group, open label, randomised controlled trial The BMJ

Published: May 15, 2024, 7 a.m.
GSK Builds Case for Broader Jemperli Label in Endometrial Cancer with Phase III Data - BioSpace

GSK Builds Case for Broader Jemperli Label in Endometrial Cancer with Phase III Data BioSpace

Published: March 18, 2024, 7 a.m.
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