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Analysis of Drug Clinical Trials in Obstetrics and Gynecology: A Five-Year Retrospective Study from a Public Tertiary Specialty Hospital in China.

Women remain underrepresented in clinical drug development despite their unique biological characteristics and growing disease burden. In China, this disparity is particularly concerning given the rising incidence of gynecologic conditions …

Published: June 30, 2026, midnight
Posterior Uterine Rupture during Pregnancy in a Patient with Previous Surgery for Severe Endometriosis: A Case Report.

Deep infiltrating endometriosis (DIE) is a severe pathology requiring complex pelvic surgery, which carries a rare but serious risk of uterine rupture during pregnancy. We report a primiparous patient who …

Published: June 30, 2026, midnight
Clinical characteristics of different subtypes of adenomyosis in infertility.

This study aimed to compare the clinical histories and clinicopathological characteristics between internal and external adenomyosis (ADM) among infertile women. A total of 759 infertile patients aged 24 to 40 …

Published: June 28, 2026, midnight
The Follicular Immune Checkpoint: PD-1/PD-L1 and Immune Tolerance in Oocyte Competence and IVF Failure.

Oocyte formation occurs successfully within a meticulously controlled follicular environment characterized by well-documented endocrine, metabolic, and paracrine signals. Yet, the immunological landscape of the follicle and its role in influencing …

Published: June 24, 2026, midnight
Rupture of the uterine artery pseudoaneurysm causing late postpartum hemorrhage: case report and literature review.

Postpartum hemorrhage (PPH) remains one of the leading causes of maternal mortality worldwide. A rare but potentially life-threatening cause of secondary PPH is uterine artery pseudoaneurysm (UAP). In this case …

Published: June 18, 2026, midnight
Placenta Accreta Spectrum Risk in Endometriosis: A Retrospective Cohort Study with ART Subanalysis.

Background/Objectives: This study assessed whether endometriosis is associated with an increased risk of placenta accreta spectrum (PAS) disorders and investigated if assisted reproductive technology (ART) further increases the risk in …

Published: June 17, 2026, midnight
The role of IL-33/ST2 signaling in female reproductive diseases.

Female reproductive tissues repeatedly undergo controlled inflammation, immune adaptation, and tissue repair. Interleukin-33 (IL-33) and its receptor suppression of tumorigenicity 2 (ST2) sit at the center of these processes, but …

Published: June 12, 2026, midnight
Assessment of Mycotoxin Exposure in Women Undergoing Assisted Reproduction: A Study of Urinary Biomarkers Related to Oocyte and Embryo Development.

Mycotoxins are widespread food contaminants, and urinary biomarkers reflect recent dietary exposure. Although mycotoxins have been implicated in reproductive toxicity, their impact on human oocyte and embryo development remains poorly …

Published: May 26, 2026, midnight
Decidualization potential of endometrial mesenchymal stem cells and their role in reproductive health.

The establishment of a successful pregnancy depends on proper embryo development and coordinated endometrial differentiation, particularly through the process of decidualization. Mesenchymal stem/stromal cells (MSCs), especially those derived from endometrial …

Published: May 23, 2026, midnight
Association between preeclampsia and eclampsia in black women with endometriosis: a scoping review.

Women with endometriosis are at increased risk of preeclampsia and eclampsia, leading causes of maternal mortality among Black women in the United States. Despite this, Black women are significantly underdiagnosed …

Published: May 22, 2026, midnight
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