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Oriva: Targeting the endometriosis trifecta - BioCentury

Oriva: Targeting the endometriosis trifecta BioCentury

Published: July 16, 2026, 12:14 a.m.
Comprehensive transcript and protein profiling reveals ERα rather than ERβ as the predominant estrogen receptor in human endometriotic lesions.

Endometriosis (EMS) is a chronic estrogen-dependent inflammatory disease. Although several studies have suggested a key role for estrogen receptor ERβ in EMS lesion development, its detection has been challenged by …

Published: July 11, 2026, midnight
Shamita Shetty opens up about horrific pain of undiagnosed endometriosis: Realised something was seriously wrong when... | Health - Hindustan Times

Shamita Shetty opens up about horrific pain of undiagnosed endometriosis: Realised something was seriously wrong when... | Health Hindustan Times

Published: July 10, 2026, 11:42 a.m.
Metabolic remodeling of endometriosis microenvironment: Energy stress and immune evasion.

Endometriosis (EMs) is an estrogen-dependent chronic inflammatory gynecological disease characterized by ectopic growth of endometrial tissues, leading to dysmenorrhea, pelvic pain, and infertility. Although the retrograde menstruation theory clarifies the …

Published: July 9, 2026, midnight
Expression of Anion Exchanger 1 (AE1) and Its Potential Involvement in Human Granulosa Cell Physiology: An In Vitro Pilot Study.

The anion exchanger 1 (AE1), traditionally known for its role in erythrocyte anion transport and acid-base homeostasis, has recently been identified in non-erythroid tissues, suggesting broader physiological functions. In the …

Published: July 9, 2026, midnight
Reassessing the Proposed Creatine-PrP Axis in Endometriosis: Methodological and Mechanistic Considerations.

The research by Chen et al. (2024) presents an innovative hypothesis linking creatine metabolism to ferroptosis resistance in endometriotic stromal cells via PrP suppression. While conceptually valuable, methodological aspects warrant …

Published: July 6, 2026, midnight
Orchestrating the gut microbiota-mitochondrial-immune axis in gynecological diseases: mechanisms and dual-targeting therapeutic strategies.

The "gut microbiota-mitochondria axis" has become the core hub connecting the metabolism, immunity, and endocrine regulation of gynecological diseases. In this review, the hierarchical regulation mechanism of this axis is …

Published: July 1, 2026, midnight
A Review of Robotic vNOTES Surgery: Current Applications, Advantages, and Future Directions.

Over the past 500 years, the convergence of three distinct paths - vaginal surgery, laparoscopy, and robotic technologies - has enabled the development of robot-assisted vaginal natural orifice transluminal endoscopic …

Published: June 30, 2026, midnight
Vitamin D3 promotes regression of endometrial implants comparable to buserelin in a rat model of endometriosis.

Buserelin, a gonadotropin-releasing hormone agonist, reduces gonadotropin and estrogen levels and is commonly used to alleviate the symptoms of endometriosis. Vitamin D3 has been reported to exhibit anti-inflammatory and pro-apoptotic …

Published: June 30, 2026, midnight
Tokishakuyakusan suppresses endometriosis and may be associated with improved fertility during attempts to conceive: A mouse model study.

Tokishakuyakusan (TSS), a traditional Japanese Kampo medicine, is known for its anti-inflammatory and anti-angiogenic properties. This study examined the effects of TSS on fecundity and endometriosis-like lesions during pregnancy in …

Published: June 30, 2026, midnight
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