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Post-marketing safety profile of Myfembree in approved gynecologic indications: a disproportionality analysis based on the FAERS database.

Myfembree, a fixed-dose combination of relugolix, estradiol, and norethindrone acetate, is approved for premenopausal women with heavy menstrual bleeding associated with uterine fibroids and moderate to severe pain associated with …

Published: Sept. 24, 2026, midnight
Prediction models for endometriosis-associated ovarian malignancy: A systematic review and meta-analysis.

Endometriosis is benign, but it is associated with an increased risk of clear-cell and endometrioid ovarian carcinoma. Several multivariable prediction models have been developed to identify malignant transformation or differentiate …

Published: Sept. 23, 2026, midnight
Evaluating the Effects of a Health Action Process Approach (HAPA)-Based Intervention on Adolescents' Menstrual Health Behaviors.

PurposeThis study evaluated the effects of a school-based intervention grounded in the Health Action Process Approach (HAPA) on adolescents' intentions to seek medical consultation for menstrual health concerns.DesignQuasi-experimental pre-post intervention …

Published: Sept. 22, 2026, midnight
Methodological Pitfalls in Endometriosis Biospecimen Research: Lessons From MAP4K4 Expression Studies.

Endometriosis is a chronic inflammatory condition affecting 10% of reproductive-age women. Current treatments remain limited and non-curative. While its biology is largely informed by human biospecimens, sample heterogeneity and methodological …

Published: Sept. 21, 2026, midnight
Evaluating potential risk factors linked to endometriosis: Evidence from a Mendelian randomization study.

Earlier examinations of how risk factors relate to endometriosis (EMT) have largely depended on observational designs, which arrived at conflicting conclusions. The present approach seeks to probe the causal association …

Published: Sept. 20, 2026, midnight
Estrogens hypersensitivity syndrome in endometriosis.

Objectives. The aim of the study was to develop a diagnostic method for estrogen hypersensitivity syndrome in proliferative benign diseases of the female reproductive system. Using the example of endometriosis, …

Published: Sept. 19, 2026, midnight
Re-Analysis of Public Transcriptomes Identifies a Candidate Histone-Cluster Signal in Eutopic Endometrium: A Hypothesis-Generating Link to Chronic Pelvic Pain.

Endometriosis is a leading cause of chronic pelvic pain (CPP), but the public transcriptomic datasets analysed here contain no pain phenotype, links to CPP are therefore hypothesis-generating.

Published: Sept. 19, 2026, midnight
Single-Cell RNA Sequencing Reveals Immune Dysregulation and Candidate Drug Targets in Endometriosis.

Endometriosis is a chronic inflammatory disorder affecting 5-10% of women of reproductive age and is associated with chronic pain and infertility. While research has mainly focused on local lesions, systemic …

Published: Sept. 19, 2026, midnight
Lifestyle factors and symptom burden in endometriosis: an exploratory mixed-methods analysis of nutrition, physical activity, and psychosocial well-being.

Endometriosis affects approximately 10% of reproductive-age women worldwide, with symptom burden significantly impacting quality of life. While current treatment guidelines focus primarily on hormonal and surgical interventions, the role of …

Published: Sept. 17, 2026, midnight
Ultrasound Sliding Sign Assessed by Transvaginal or Transrectal Route for Predicting Complete Pouch of Douglas Obliteration in Patients with Ovarian Endometriomas: An Exploratory Retrospective Study.

Background and Objective: The ultrasound sliding sign dynamically assesses pouch of Douglas (POD) obliteration in suspected endometriosis. Transvaginal (TVS) and transrectal (TRS) ultrasound are used in patients with and without …

Published: Sept. 17, 2026, midnight
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