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Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry.

Anxiety is heritable and exists on a continuum, with symptoms ranging from adaptive threat response to clinical disorder. Here we performed a genome-wide association meta-analysis of generalized anxiety symptom severity …

Published: June 9, 2026, midnight
Breaking the endometriosis-stroke axis: lesion-focused hydrogel reprogramming of thromboinflammatory networks.

Endometriosis is a chronic, systemic inflammatory disorder characterized by the ectopic implantation of endometrial-like tissue and accompanied by persistent pain and infertility. Beyond the pelvis, accumulating epidemiological evidence indicates that …

Published: June 8, 2026, midnight
Neurovascular architecture of deep endometriosis and postoperative pain outcomes after butterfly peritoneal excision, a prospective pilot study.

To evaluate the neurovascular architecture of deep endometriosis using a standardized butterfly excision approach and to explore its association with postoperative pain outcomes.

Published: June 7, 2026, midnight
Surgically confirmed severe endometriosis is associated with lower risk of steatotic liver disease: Evidence of estrogen-linked hepatic-reproductive crosstalk.

The prevalence of steatotic liver disease (SLD) is increasing globally. Endometriosis, affecting up to 10% of women, is a major cause of infertility. While associations between endometriosis and metabolic syndrome …

Published: June 6, 2026, midnight
Gut microbiota dysbiosis in endometriosis: mechanistic insights and gut microbiota-targeted therapeutic strategies.

Endometriosis (EMs) is a prevalent, estrogen-dependent gynecological disorder characterized by the ectopic implantation and proliferation of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of reproductive-aged women globally. Despite …

Published: June 5, 2026, midnight
Gut-reproduction axis: genome-wide pleiotropic and prospective evidence linking inflammatory bowel disease with gynecological disorders.

We aimed to explore shared genetic architectures and potential causal associations between inflammatory bowel disease (IBD) and gynecological diseases, including ovarian cysts (OC), pelvic inflammatory disease (PID), and endometriosis (EMs), …

Published: June 4, 2026, midnight
Psychological flexibility and pain catastrophizing in endometriosis: Incremental validity and interaction effects in predicting psychosocial outcomes.

Psychological distress and reduced health-related quality of life are common among women with endometriosis, particularly when the condition is accompanied by chronic pain. Psychological flexibility (PF), a core process in …

Published: June 4, 2026, midnight
Hypoxia-induced regulations of cell adhesion molecules and their implications for pathogenesis, diagnosis, and treatment of endometriosis.

Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial-like tissue outside the uterine cavity, affecting up to 10% of women of reproductive age. Despite extensive research, its …

Published: June 4, 2026, midnight
Executive Functions Mediate Between Endometriosis Burden and Women's Daily Life.

To examine (1) group differences in executive functioning, disease burden, occupational balance and quality of life between women with endometriosis and healthy controls; (2) associations between pain-related and psychological disease …

Published: June 3, 2026, midnight
Infertility and age of menopause in a longitudinal cohort of women with primary infertility.

To analyze the association between primary infertility and infertility type with the age of natural menopause.

Published: June 2, 2026, midnight
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