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Patient-derived organoids in gynaecological cancers: emerging tools for therapy and disease modelling.

Patient-derived organoids (PDOs) have emerged as physiologically relevant three-dimensional (3D) culture systems that closely mimic the molecular and histological features of the human endometrium and associated malignancies. Owing to their …

Published: June 27, 2026, midnight
A case of omental endometriosis complicated by hemorrhagic ascites leading to pelvic encapsulated effusion.

Endometriosis is an estrogen-dependent benign inflammatory disorder characterized by the implantation of active endometrial tissue (glands or stroma) outside the uterus, with pelvic adhesions as a core hallmark. Omental endometriosis …

Published: June 23, 2026, midnight
Histone lactylation: a novel epigenetic bridge linking cellular metabolism to benign and malignant gynecological diseases.

Lactic acid modification of histones represents an emerging post-translational modification that establishes a critical link between cellular metabolic reprogramming and epigenetic regulation through the covalent binding of lactic acid to …

Published: June 23, 2026, midnight
Risk factors for postoperative opioid prescription after benign hysterectomy.

To identify risk factors for dispensed opioid prescriptions after benign hysterectomy.

Published: June 23, 2026, midnight
Serum Interleukin-6 Levels in Endometriosis and Endometriosis-Associated Ovarian Cancer: A Systematic Review and Meta-Analysis Demonstrating a Biological Gradient.

This study quantifies serum/plasma interleukin-6 levels across the healthy-non-endometriosis benign-endometriosis-ovarian cancer spectrum, focusing on pooled geometric means stratified by control type.

Published: June 21, 2026, midnight
A Rare Coexistence: Uterine Leiomyoma Arising in a Mature Cystic Teratoma and a Pedunculated Endometriotic Cyst Mimicking Leiomyoma-Two Case Reports.

Uterine leiomyomas are common benign tumors, but their clinical presentation can be misleading. We report two unusual cases of pedunculated uterine masses presenting with heavy vaginal bleeding. In the first …

Published: June 21, 2026, midnight
Path beyond the blind end-unravel the imaging spectrum of appendiceal pathologies.

The appendix is involved in a diverse spectrum of inflammatory, infectious, benign, and malignant conditions that extend far beyond acute appendicitis. Although acute appendicitis remains the most common appendiceal emergency, …

Published: June 20, 2026, midnight
Case Report: Malignant transformation of deep infiltrating endometriosis: a report of two cases and literature review.

Deep infiltrating endometriosis (DIE) is a severe form of endometriosis that rarely undergoes malignant transformation, and when it does, diagnosis is often difficult. Here, we report two cases of long-standing …

Published: June 18, 2026, midnight
Complex benign gynecology in perimenopause: current evidence and future directions.

Perimenopause is a clinically distinct stage in which abnormal uterine bleeding, fibroids, adenomyosis, endometriosis, and adnexal pathology may require surgical evaluation. Management is complex because symptom burden and structural disease …

Published: June 17, 2026, midnight
Cross-Platform Comparison of Hugo RAS and da Vinci Xi in Benign Robotic Hysterectomy: Differences in Cost Structure and Operative Time.

To compare perioperative outcomes and hospital cost structure between Hugo RAS and da Vinci Xi for benign simple hysterectomy using a common institutional accounting framework.

Published: June 17, 2026, midnight
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