Latest Articles

Roles of Goserelin in Gynecological Disorders.

Goserelin is a gonadotropin-releasing hormone (GnRH) agonist with a long history of clinical application and well-established efficacy and safety profile. Its mechanism of action centers on sustained GnRH receptor desensitization, …

Ovarian preservation in a pregnant woman with a leaking dermoid cyst and ovarian torsion: a case study and review of diagnostic and therapeutic challenges.

Ovarian cysts are common during pregnancy, and dermoid cysts are common benign ovarian tumors, affecting approximately 0.3% of pregnancies, most often detected in the second trimester. Hormonal changes and pressure …

Correlations Between Ultrasound Features and Histological Findings in Adenomyosis: A Single-Center Retrospective Study.

Adenomyosis is a benign gynecologic condition characterized by ectopic endometrial glands and stroma present within the myometrium. Background/Objectives: The gold standard in diagnosis is the histology of hysterectomy specimens. Due …

Cancer-like Hallmarks of Endometriosis: The Role of Estrogen Signaling and Stem Cell Plasticity.

Endometriosis is a chronic estrogen-dependent inflammatory disease affecting approximately 10% of women of reproductive age and characterized by ectopic endometrial-like tissue growth. Although traditionally considered a benign gynecological condition, increasing …

Nuclear factor IX promotes endometriosis progression through transcriptional activation of tetraspanin-2.

Endometriosis is a benign yet aggressive disease characterized by enhanced proliferation and invasion of ectopic endometrial tissue. Identifying upstream regulators that co-regulate these processes will provide novel insights into endometriosis …

Insights from an observational matched case-control study on the association between endometriosis and benign uterine disorders in infertile patients.

The link between endometriosis and other medical conditions is gaining attention. Such insights could enhance clinical approaches to manage the disease and potentially reveal new, unrecognized mechanisms of its development. …

Genomic insights into endometriosis, adenomyosis, and uterine fibroids for the clinician.

Over the last few decades, genomics has become integral to understanding disease pathophysiology, improving diagnostics, and refining treatment strategies. Endometriosis, uterine fibroids, and adenomyosis are highly prevalent benign gynecologic disorders …

Transition from pediatric and adolescent gynecology to complex benign gynecology - who, what, and when?

The purpose of this article is to provide a comprehensive review of recent literature addressing diagnoses and conditions that intersect pediatric and adolescent gynecology (PAG) and complex benign gynecology (CBG) …

When benign mimics malignancy: a call for surgical restraint and clinical nuance in endometriosis-associated ovarian masses.

Transfer RNA-derived small RNAs in female reproductive disorders: emerging roles and clinical implications.

Female reproductive disorders present significant challenges worldwide. Transfer RNA-derived small RNAs (tsRNAs), a structurally diverse class of non-coding RNAs mainly comprising tRNA halves (tiRNAs) and tRNA-derived fragments (tRFs), have emerged …