Latest Articles

Adnexectomy at Vaginal Hysterectomy for Benign Non-prolapse Indications: A National NSQIP Analysis of Practice Patterns and Perioperative Outcomes.

Professional societies recommend opportunistic salpingectomy during vaginal hysterectomy to reduce the risk of ovarian cancer, but it may be technically challenging without uterine prolapse. We examined national patterns, patient and …

Integrating quality of life instruments into clinical care for benign gynecological conditions to enhance patient-centered care.

The quality-of-life (QoL) impacts of benign gynecological conditions, such as polycystic ovarian syndrome (PCOS), endometriosis, and uterine fibroids on patients' lives are underestimated. Upon analysis of the 36-Item Short Form …

Innervation of the Uterus: An Anatomical Study With Application to Better Understanding Pelvic Pain in Women.

Pelvic pain has a significant impact on quality of life, especially when associated with benign pelvic diseases, such as endometriosis or chronic conditions leading to persistent discomfort. A substantial proportion …

Hidden Burden of Fallopian Tube Endometriosis: Prevalence and Associations with Pelvic Pathology.

Background/Objectives: Fallopian tube endometriosis is frequently underreported due to its nonspecific presentation, limitations in imaging detection, and the fact that histologic diagnosis often requires the submission of the entire fallopian …

Surgical Outcomes and Learning Curve of Robotic Single-Port Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Hysterectomy Using the Da Vinci Single-Port System.

This study aims to assess the surgical outcomes and learning curve of robotic single-port vaginal natural orifice transluminal endoscopic surgery (RSP-vNOTES) for hysterectomy in benign gynecologic conditions.

Why Are We Still Talking About Endometriosis? A Call for Structural Change in Complex Benign Gynecologic Care.

The effect of tinzaparin sodium and leuprolide acetate in an experimental mouse model of endometriosis: The rol of the WNT/beta-catenin pathway.

Endometriosis is a benign condition driven by estrogen and inflammation in which endometrial-like tissue develops in ectopic locations. We aimed to determine whether non-steroidal agents acting on the WNT/beta-catenin signaling …

Repurposing ramipril to mitigate EMT-like transition in endometriosis by PI3K/AKT/S6K1 signalling pathway: a study in endometriosis induced rats.

Endometriosis, an atypical benign disorder, may disrupt epithelial-mesenchymal transition (EMT) due to a dysregulated balance between matrix metalloproteinases (MMPs) and their inhibitors. Ramipril, an angiotensin converting enzyme (ACE) inhibitor, is …

Beneficial Effects of Fisetin, a Senotherapeutic Compound, in Women's Reproductive Health and Diseases: Evidence from In Vitro to Clinical Studies.

Fisetin is a naturally occurring flavonoid, a type of polyphenol found in fruits and vegetables such as strawberries, apples, persimmons, and onions. It has gained increasing attention for its antioxidant …

Pure non-gestational ovarian choriocarcinoma in a postmenopausal woman coexisting with a clear cell adenofibroma and endometriosis foci: A case report and review of the literature.

Ovarian germ cell tumours are uncommon, with choriocarcinoma being the rarest of them. Among choriocarcinomas, the non-gestational type occurs mainly in premenarchal women, although cases have been described in postmenopausal …