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Expanding the genetic landscape of endometriosis: Integrative -omics analyses implicate key genes and pathways in a multi-ancestry study of over one million women.

We report the findings of a genome-wide association study (GWAS) meta-analysis of endometriosis across 14 biobanks worldwide, including 32% non-European patient participants, as part of ​the ​Global Biobank Meta-Analys​i​s Initiative​ …

Published: Dec. 4, 2025, midnight
Bidirectional Mendelian randomization and cross-sectional study reveal depression as a causal risk factor for endometriosis.

Endometriosis (EMs) and depression are both common conditions that have a significant negative impact on quality of life. However, it is still unclear about the relationship between them. The study …

Published: Nov. 21, 2025, midnight
Proteome-wide Mendelian randomization identifies β-nerve growth factor as a target for endometriosis.

Endometriosis is a chronic inflammatory disorder with poorly understood mechanisms. Inflammatory proteins are hypothesized to play a causal role, but evidence remains limited. We performed a 2-sample Mendelian randomization study …

Published: Nov. 16, 2025, midnight
Register and biobank on influence of assisted reproduction on pregnancy, maternal and neonatal outcome : A prospective multicenter medical data register and biobank.

Infertility affects 10-15% of couples worldwide. In Austria, the In Vitro Fertilization Fund supports assisted reproductive technology under specific conditions. While assisted reproductive technology is generally effective, its impact on …

Published: Oct. 7, 2025, midnight
The Translation and Cross-Cultural Adaptation of The Persian Version of The WERF EPHect Endometriosis Patient Questionnaire: A Cross-Sectional Study.

The World Endometriosis Research Foundation (WERF) Endometriosis Phenome and Biobanking Harmonisation Project (EPHect) aims to facilitate international research on endometriosis by developing a standardized questionnaire. This study focuses on translating …

Published: Sept. 30, 2025, midnight
Correction to: WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Homologous): homologous rodent models.

Published: Aug. 27, 2025, midnight
Correction to: WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Heterologous): heterologous rodent models.

Published: Aug. 27, 2025, midnight
DRIVE-KG: Enhancing variant-phenotype association discovery in understudied complex diseases using heterogeneous knowledge graphs.

Multi-omics data are instrumental in obtaining a comprehensive picture of complex biological systems. This is particularly useful for women's health conditions, such as endometriosis which has been historically understudied despite …

Published: Aug. 21, 2025, midnight
Associations between biological aging and the risk of endometriosis: Evidence from a large population-based prospective cohort study.

Endometriosis is a common disease for women of reproductive ages. Individuals with accelerated biological aging are at a higher risk of developing various diseases, however, the effect of biological aging …

Published: July 24, 2025, midnight
The association of activity patterns on female reproductive diseases: a prospective cohort study of UK biobank.

Little is known about the role of timing of physical activity in female reproductive disorders. These disorders include polycystic ovary syndrome (PCOS), heavy menstrual bleeding (HMB), endometriosis, infertility, and pregnancy-related …

Published: Jan. 24, 2025, midnight
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