Epithelial ovarian cancer is not a single disease but a group of biologically distinct malignancies that include serous (high-grade and low-grade), endometrioid, clear cell, and mucinous carcinomas, along with other …
Ovarian clear cell carcinoma (OCCC) frequently arises in association with endometriosis and is characterized by iron-rich oxidative stress, hypoxia-responsive metabolic reprogramming, glycogen accumulation, and alterations in ferroptosis-regulatory pathways. Interactions among …
Background: Endometriosis-associated ovarian cancers (EAOCs), including ovarian clear cell (OCCC) and endometrioid ovarian carcinoma (EnOC) subtypes, frequently exhibit transcriptomic dysregulation of the PI3K/AKT/mTOR signalling axis. While genomic aberrations are well-documented, …
Colorectal Carcinoma Metastatic to the Breast Mimicking Inflammatory Breast Cancer With Mismatch Repair Status Discordant From a Prior Endometrial Primary: A Case Report and a Review of the Literature Cureus
To compare clinical features, treatment responses, and survival outcomes between endometriosis-associated ovarian cancer (EAOC) and high-grade serous ovarian carcinoma (HGSOC), with a focus on platinum resistance.
Malignant transformation of endometriosis is rare and most commonly involves the ovary. Extraovarian transformation, particularly in the gastrointestinal tract, is exceptional, and clear cell carcinoma (CCC) arising from intestinal endometriosis …
Mismatch Repair Protein Expression in Endometrial Intraepithelial Neoplasia and Endometrial Carcinoma: Experience From a Tertiary Care Hospital Cureus
Ovarian Carcinoma Presenting Mucoepidermoid Carcinoma-Like Features in Association With Seromucinous Borderline Tumor: A Real Seromucinous Carcinoma? Cureus
Ovarian seromucinous carcinoma is generally classified within the spectrum of endometrioid carcinoma. We report a rare ovarian carcinoma with mucoepidermoid carcinoma-like features arising in direct association with a seromucinous borderline …
Intestinal endometriosis is a benign gynecological condition that frequently involves the rectosigmoid colon. Its synchronous occurrence with colorectal cancer is exceptionally rare and diagnostically challenging, particularly when mimicking a second …