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A new perspective on endometriosis: Integrating eQTL mendelian randomization with transcriptomics and single-cell data analyses.

Endometriosis is caused by the migration of endometrial cells to locations outside the uterine lining. Despite the increasing prevalence of endometriosis, there has been limited research on genetic effects, and …

Published: March 26, 2025, midnight
The effect of norethisterone acetate on the uterine telocytes, immune cells and progesterone receptors in albino rats.

This study is the first attempt to examine the effects of NETA on immune cells and telocytes. The results of this study form an important knowledge base for the development …

Published: March 15, 2025, midnight
Extracellular vesicles in endometrial-related diseases: role, potential and challenges.

Endometrial dysfunction underlies many common gynecologic disorders, such as endometriosis, endometrial cancer, intrauterine adhesions, and endometritis, which affect many women around the world. Extracellular vesicles play an important role in …

Published: March 12, 2025, midnight
GRB2 regulation of essential signaling pathways in the endometrium is critical for implantation and decidualization.

Over 75% of failed pregnancies involve implantation defects. Growth factor receptor-bound protein 2 (GRB2) is an adaptor protein involved in signal transduction and cell communication. Here we show that the …

Published: March 4, 2025, midnight
A case of deep endometriosis with cyst formation as a differential diagnosis of rectal duplication cyst in the presacral space.

Cysts occurring in the presacral space may become malignant and therefore require surgical removal. A wide variety of cystic lesions can occur in the presacral space, such as tailgut cysts, …

Published: Feb. 12, 2025, midnight
Endometriosis influencers on Instagram: Who are they and what are they posting?

To examine endometriosis-related content on Instagram, a platform increasingly used for health communication, to understand: 1) the identity of Instagram content creators; 2) themes, tones, and emotions evoked from posts; …

Published: Feb. 6, 2025, midnight
Ovarian Endometrioma Disrupts Oocyte-Cumulus Communication and Mitochondrial Function, With Melatonin Mitigating the Effects.

Ovarian endometrioma (OEM), a particularly severe form of endometriosis, is an oestrogen-dependent condition often associated with pain and infertility. The mechanisms by which OEM impairs fertility, particularly through its direct …

Published: Jan. 21, 2025, midnight
Associations between health-related quality of life, infertility-related psychological well-being, and relationship quality in individuals with endometriosis: A cross-sectional study.

Endometriosis is the most frequent gynecological diseases and accompanied by both physical and psychological symptoms. An increasing number of studies suggested acknowledging endometriosis as a systematic disease due to the …

Published: Dec. 21, 2024, midnight
Unraveling the complexity of follicular fluid: insights into its composition, function, and clinical implications.

Follicular fluid (FF) plays a vital role in the bidirectional communication between oocytes and granulosa cells (GCs), regulating and promoting oocyte growth and development. This fluid constitutes a complex microenvironment, …

Published: Nov. 26, 2024, midnight
"No doctor ever asked me…so I thought it wasn't a valid concern": endometriosis patients' perspectives of barriers and facilitators to sexual health communication in general practice.

Sexual health communication between general practitioners (GPs) and individuals with chronic diseases is well documented as an important component of sexual well-being. However, a notable gap exists in understanding factors …

Published: Nov. 14, 2024, midnight
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