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The Endocannabinoid System in Endometriosis-Associated Pain: Mechanisms, Molecular Targets, and Therapeutic Implications.

Endometriosis is a chronic gynecological disorder affecting approximately 10% of reproductive-age women, characterized by the ectopic growth of endometrial tissue and severe pain, including dysmenorrhea, chronic pelvic pain, dyspareunia, dysuria, …

Published: Sept. 15, 2026, midnight
NRF2 Signalling in Endometriosis: A Hormone-Independent Axis for Fertility-Preserving Therapeutic Innovation.

Endometriosis is a chronic inflammatory disease characterised by pain, infertility and recurrence. Current pharmacological management relies largely on hormonal suppression, which can reduce pain and disease activity but does not …

Published: Sept. 14, 2026, midnight
Compartment-specific inflammation-metabolism remodeling across eutopic and ectopic endometriosis tissues with cross-context evaluation in TCGA-UCEC.

Endometriosis exhibits tissue- and cell-compartment heterogeneity in inflammatory and metabolic activity. We evaluated compartment-specific remodeling in primary endometriosis tissues and used TCGA-UCEC as an independent cancer comparison.

Published: Sept. 12, 2026, midnight
Diagnostic and Predictive Values of Ferroptosis-Related Genes in Endometriosis Based on Integrated Bioinformatic Analysis.

Endometriosis (EMs) is a prevalent gynecological disorder. Ferroptosis, known as a novel type of programmed cell death, contributes to EMs pathogenesis by promoting ectopic endometrial migration. This study was designed …

Published: Sept. 11, 2026, midnight
[Inhibitory effect of phloroglucinol on eutopic stromal cells and ectopic stromal cells from endometriosis and its mechanism].

Objective: To investigate the inhibitory effects of phloroglucinol on eutopic stromal cells and ectopic stromal cells from endometriosis and its molecular mechanism. Methods: The effect of phloroglucinol on the survival …

Published: Sept. 9, 2026, midnight
Deciphering the Role of ZEB1 as a Central Regulator of Epithelial-Mesenchymal Transition and Hormonal Resistance in Endometriosis.

Endometriosis is a chronic inflammatory and sex steroid hormone-dependent gynaecologic disease, characterised by endometrial cell proliferation outside the uterine cavity, often accompanied by fibrosis, progesterone resistance, and high recurrence despite …

Published: Sept. 9, 2026, midnight
TCM Treatment of Endometriosis: Pathogenesis, Mechanism and Clinical Practice.

Endometriosis (EMs) is a chronic neuroinflammatory disorder prevalent in women of reproductive age characterized by heterogeneous clinical manifestations, while conventional Western therapies are limited by obvious adverse reactions and unsatisfactory …

Published: Sept. 9, 2026, midnight
Ectopic Endometrium-Targeted M1 Macrophage-Derived Nanovesicles for Treatment of Endometriosis.

Endometriosis (EMs) is a common gynecological disorder in women of reproductive age, often presenting with pelvic pain and infertility. Its progression is closely linked to estrogen levels. While hormonal therapies …

Published: Sept. 8, 2026, midnight
Uterine Müllerianosis.

Introduction: Müllerianosis is a rare pathological entity characterized by ectopic Müllerian-derived tissues, including endometrium, endocervix, and/or endosalpinx. Most reported cases involve the urinary bladder, while uterine involvement is extremely uncommon. …

Published: Sept. 7, 2026, midnight
Modulating the Estrobolome and Inflammatory Microenvironment in Endometriosis: The Role of Microbiome-Targeted Interventions and Nutritional Compounds.

Endometriosis is a chronic estrogen-dependent systemic inflammatory disorder characterized by ectopic implantation of endometrial-like tissue, primarily on the ovaries, pelvic peritoneum, and bowel. According to the World Health Organization (WHO) …

Published: Sept. 3, 2026, midnight
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