Andrographolide blocked the progression of endometriosis by promoting ferroptosis via inhibiting anabolism of serine.
Ferroptosis is a potential target for the treatment of endometriosis (EMs). The role of andrographolide (AP) in the ferroptosis has gradually attracted attention, but its mechanism of action in endometriosis …
Compound design of a patient-derived 3D cell culture system modelling early peritoneal endometriosis.
Peritoneal endometriosis causes pelvic pain and infertility, but the underlying mechanisms related to these symptoms are not fully understood. Endometriosis diagnosis is typically delayed; thus, patient samples are unsuitable to …
Delayed onset of HPV-associated uterine malignancies: seven pathogenetic factors in contrast to cervical cancer.
Human papillomavirus (HPV) is a well-established etiological agent for cervical cancer, yet its contribution to endometrial malignancies remains underrecognized and mechanistically distinct. This paper synthesizes current evidence to explain the …
Transcriptional coregulator ZMIZ1 modulates estrogen responses that are essential for healthy endometrial function.
Estrogen is a critical regulator of endometrial health. Aberrant estrogen stimulation can result in infertility, endometrial cancer, and endometriosis. Here, we identified Zinc Finger MIZ-Type Containing 1 (Zmiz1) as a …
Endometrial Stromal Cells from Endometriosis Patients Reflect Lesion-Type-Specific Heterogeneity.
Endometriosis, a disease affecting about one out of ten women, is characterized by the growth of endometrial-like tissue outside the uterine cavity. There is significant disease heterogeneity, but the pathophysiological …
High-Intensity Focused Ultrasound (HIFU) as a Combined Approach for the Treatment of Recurrent Low-Grade Endometrial Stromal Sarcoma: A Case Report and Literature Review - Frontiers
High-Intensity Focused Ultrasound (HIFU) as a Combined Approach for the Treatment of Recurrent Low-Grade Endometrial Stromal Sarcoma: A Case Report and Literature Review Frontiers
Reproductive tract microbiota dysbiosis in ovarian endometrioma and adenomyosis: multi-site 16S rRNA profiling and functional impact of key bacterial species on human endometrial stromal cells.
Low-grade endometrial stromal sarcoma arising from extrauterine deep infiltrating endometriosis: a rare, but important differential diagnosis and short review of the literature.
Low-grade endometrial stroma sarcoma is a very rare mesenchymal neoplasm, that is usually found inside the uterine corpus. It is very uncommon that LG-ESS arises from extrauterine foci.