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Vitamin D and Endometriosis: Is There a Mechanistic Link?

Endometriosis is a prevalent chronic gynaecological disorder, but its cause is still unclear, and both genetic and environmental factors may contribute disease aetiology. Prominent amongst the latter is vitamin D …

Published: Jan. 2, 2025, midnight
The Role of Inflammatory Markers NLR and PLR in Predicting Pelvic Pain in Endometriosis.

Background/Objectives: Chronic inflammation plays a critical role in pelvic pain among endometriosis patients. This study examines the association between inflammatory markers-specifically the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR)-and pelvic …

Published: Dec. 30, 2024, midnight
Dyspareunia and Biomarkers: A Case Study of Sexual Dysfunction in Moderate Endometriosis.

Endometriosis, a chronic hormone-dependent condition affecting 10% of women globally, impacts pelvic organs and occasionally distant sites, causing pain, infertility, and sexual dysfunction. Biomarkers such as IL-8, IL-10, and BDNF …

Published: Dec. 27, 2024, midnight
Single-Cell RNA Sequencing of PBMCs Identified Junction Plakoglobin (JUP) as Stratification Biomarker for Endometriosis.

This study aimed to identify unique characteristics in the peripheral blood mononuclear cells (PBMCs) of endometriosis patients and develop a non-invasive early diagnostic tool. Using single-cell RNA sequencing (scRNA-seq), we …

Published: Dec. 5, 2024, midnight
Identification of predictors for acute postoperative pain after gynecological laparoscopy (STROBE-compliant article).

While the pain after gynecological laparoscopy is assumed to be minor, many women suffer from unexpected postoperative pain in the post-anesthesia care unit (PACU). Prior identification of these patients is …

Published: Oct. 14, 2024, 1:26 p.m.
Feasibility of Predicting Surgical Duration in Endometriosis Using Numerical Multi-Scoring System of Endometriosis (NMS-E).

Endometriosis is a multifaceted gynecological condition that poses diagnostic challenges and affects a significant number of women worldwide, leading to pain, infertility, and a reduction in patient quality of life …

Published: June 6, 2024, midnight
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