Endometriosis is an estrogen-driven, inflammatory disorder affecting ~10% of menstruators, causing severe pain. Current treatments that reduce estrogen or inflammation have inconsistent efficacy and poor tolerability. Therapies identified via drug-repositioning …
Myfembree, a fixed-dose combination of relugolix, estradiol, and norethindrone acetate, is approved for premenopausal women with heavy menstrual bleeding associated with uterine fibroids and moderate to severe pain associated with …
A woman in her 20s presented with severe progressive dysmenorrhoea that began within 1-2 years of menarche, was refractory to medical therapy and required repeated emergency department visits for parenteral …
To examine the epistemic injustice experienced by a gender diverse individual during diagnosis for chronic pelvic pain and endometriosis.
Women with endometriosis often face difficulty becoming pregnant, mainly when their ovaries produce only a small number of eggs. In assisted fertility treatments, hormones are used to help eggs mature …
Angiogenesis plays a critical role in the progression of endometriosis, with enhanced glycolysis accelerating pathological angiogenesis. Prior research has identified a central role for N6-methyladenosine (m6A) modification in regulating glycolytic …
Thoracic endometriosis is an uncommon but likely underrecognized manifestation of extragenital endometriosis that can present with catamenial pneumothorax, chest pain, and respiratory symptoms. This case series reviews imaging findings from …
Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by ectopic endometrial-like glands and stroma, persistent pelvic inflammation, pain, infertility, and frequent recurrence. The limited availability of nonhormonal and lesion-directed therapies …
Endometriosis is a chronic gynecological disorder characterized by persistent pain and impaired quality of life, with limited effective treatment options. Emerging evidence indicates that cannabinoids may provide analgesic and symptom-relieving …
Thoracic endometriosis is a rare manifestation of extra pelvic endometriosis and it is often missed because of its variable clinical presentation. A 33-year-old woman undergoing evaluation for secondary subfertility presented …