Benign uterine disorders, including uterine leiomyomas and uterine endometriosis/adenomyosis-related conditions, are common causes of gynecologic morbidity and represent an important women's health issue. Although these conditions are generally non-malignant, a …
Endometriosis is a chronic, heterogenous disorder in which cyclical hemorrhage and repetitive repair generate ectopic implants that persist, recur, and drive pain and infertility; conventional frameworks emphasizing hormonal aberration and …
Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by highly individualized, multisystemic symptoms, affecting approximately 10% of females. In this work, we present a long-term prospective study in which 34 …
Rheumatic heart disease (RHD) remains the leading cause of acquired valvular heart disease in low- and middle-income countries, affecting an estimated 40 million individuals and disproportionately affecting children and young …
The causal role of established risk factors for premenstrual disorders (PMDs) remains unclear. We used Mendelian randomization (MR) to assess causality for eight known-risk factors identified through a literature review. …
Dysmenorrhea is the most common gynaecological condition in women of reproductive age. Approximately 90% of cases are primary dysmenorrhea (PDM) which is not associated with underlying pathology. Dysmenorrhea can have …
Circadian rhythm (CR) is a 24-hour biological cycle regulated by endogenous and environmental factors. Altered CR gene expression has been associated with gestational diabetes mellitus (GDM), potentially affecting vascular regulation …
Endometriosis is a multifactorial, chronic inflammatory disorder that affects a substantial proportion of women during their reproductive years and is frequently associated with pelvic pain and infertility. Accumulating evidence suggests …
Data on long-term outcomes of surgical management of rectal endometriosis are scarce and generally provided by cohort studies where choice of surgical technique is based on various uncontrolled factors with …
Since cumulus cells (CCs) play an undeniable role in oocyte maturation by producing and transferring important molecules to the oocyte, examining these cells can provide a broad view of the …