Ovarian carcinosarcoma typically comprises high-grade carcinoma and sarcoma components. We report a case of a woman in her 40s with endometriosis-associated ovarian carcinosarcoma exhibiting an unusual presentation of well-differentiated adenocarcinoma …
Endometriosis (EMS) is a highly heterogeneous chronic gynecological disease characterized by pain, infertility, and relapse, with its etiology and pathogenesis not yet fully elucidated. Traditional theories, including "retrograde menstruation," "implantation …
Extrauterine mesonephric-like carcinoma (ExUMLC) is a rare female genital tract tumor associated with advanced stage disease and distant recurrences. Although there is a histologic and mutational overlap with extrauterine low …
Neonatal uterine bleeding (NUB) has been hypothesized as a relatively common early-life event potentially linked to the later development of endometriosis through retrograde menstruation. However, its true prevalence and biological …
Several hypotheses have been proposed to explain the establishment of endometriosis, of which retrograde menstruation remains the most widely accepted mechanism of dissemination. However, the mechanisms governing selective lesion establishment …
Preimplantation genetic testing for aneuploidy (PGT-A) is widely used to screen for embryo aneuploidy, enabling the selection and transfer of genetically normal embryos. Despite its potential to improve clinical outcomes, …
Current models of endometriosis (EMs) still have limitations in replicating the key pathological features of human EMs, particularly the cyclic bleeding associated with ectopic lesions. To address this gap, this …
Objective: To investigate optimal long-term medication regimens combined with focused ultrasound ablation surgery (FUAS) for alleviating dysmenorrhea in patients with extrinsic adenomyosis. Methods: A retrospective research enrolled patients with extrinsic …
Obstructed hemivagina and ipsilateral renal anomaly syndrome was first identified by Purslow in 1922 as a result of abnormal embryologic development of the Müllerian (paramesonephric) and Wolffian (mesonephric) ducts. The …
Ovarian function relies on a network of well-coordinated molecular mechanisms that regulate follicular development, oocyte maturation, ovulation, and corpus luteum function. When these processes are disrupted, infertility can result. Extracellular …