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Endometriosis - on the intersection of modern environmental pollutants and ancient genetic regulatory variants.

Endometriosis is a chronic, estrogen-driven inflammatory disorder affecting approximately 10% of reproductive-aged women globally. Despite increasing genomic insights into advanced-stage disease, the genetic underpinnings of early-stage endometriosis remain poorly understood, …

Published: Nov. 20, 2025, midnight
Colo-Ovarian Fistula With a Background of Endometriosis: A Report of Three Cases.

Patients with endometriosis are at a high risk of developing pelvic inflammatory disease. This case series presents three cases of colo-ovarian fistulas associated with endometriosis, highlighting the potential for conservative …

Published: Nov. 19, 2025, midnight
Peritoneal inclusion cyst causing intestinal obstruction in a 9-year-old girl: A rare pediatric case.

Peritoneal inclusion cyst (PIC) is a rare benign condition with low-risk malignant transformation that typically occurs in adult women with a history of pelvic inflammatory conditions, endometriosis, or prior abdominal …

Published: Nov. 18, 2025, midnight
How Do Australian Physiotherapists Clinically Manage People With Symptomatic Endometriosis and Vulvodynia? A Survey of Current Practice Among Australian Physiotherapists.

A growing body of evidence suggests that pelvic health physiotherapy is an effective, low-risk management strategy for women with endometriosis and vulvodynia. However, to date no study has identified which …

Published: Nov. 17, 2025, midnight
The effect of infertility-related stress on fertility-related quality of life in reproductive-age married women with endometriosis: the mediating role of family resilience.

This study investigated fertility-related quality of life among married women of reproductive age (20-45 years) with endometriosis-associated infertility, focusing on the mediating role of family resilience between infertility-related stress and …

Published: Nov. 16, 2025, midnight
Endometriosis During Peri-Menopause and Post-Menopause: A Review of the Literature.

Endometriosis is traditionally regarded as a condition predominantly affecting women of reproductive age, often associated with infertility and cyclical pelvic pain. As a result, a significant body of research and …

Published: Nov. 14, 2025, midnight
Interventions for endometriosis-related pain and infertility: a protocol for systematic review and network meta-analysis.

Endometriosis, a chronic oestrogen-dependent disorder, presents significant clinical challenges including pelvic pain, dysmenorrhoea, dyspareunia and infertility. While numerous interventions exist, evidence guiding the choice among surgical, hormonal and non-hormonal therapies …

Published: Nov. 13, 2025, midnight
Pharmacologic Interventions for Endometriosis-Related Pain: A Systematic Review and Meta-analysis.

(Abstracted from Obstet Gynecol 2025;146(2):e23-e35) An estimated 10% to 15% of women who are of reproductive age are affected by endometriosis, defined as abnormal growth of endometrium-like tissue outside of …

Published: Nov. 7, 2025, midnight
Lactate-mediated immune suppression and MDSC expansion in endometriosis: Mechanisms and nanoparticle-targeted therapies.

Endometriosis, a chronic gynecological disorder characterized by the ectopic growth of endometrial-like tissue, is associated with severe pelvic pain, infertility, and profound immune dysregulation. Despite advances in hormonal therapy and …

Published: Nov. 1, 2025, midnight
From Gut to Reproductive Health: Exploring Microbiome Interactions and Future Interventions.

Recent advances in microbiome research have illuminated the complex bidirectional interactions between gut health and reproductive well-being. Understanding the gut microbiome's influence on the reproductive system and vice versa reveals …

Published: Oct. 31, 2025, midnight
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