Can patient-derived organoid models be reliably established from diverse surgical phenotypes of endometriosis, and how do clinical factors such as hormonal treatment affect their growth success and morphology?
This study explores the relationship between inflammatory biomarkers and the risk of endometriosis, aiming to develop a predictive model using National Health and Nutrition Examination Survey (1999-2006) data. The dataset …
We aimed to generate immortalized stromal cell lines from the ovarian and fallopian tube tissues of a single patient using Sendai virus (SeV) vectors and identify candidate stromal genes involved …
Ovarian fibrosis is increasingly recognized as a pivotal factor contributing to ovarian aging, dysfunction and female infertility. It results from chronic or repetitive ovarian injury, such as that caused by …
This study evaluated the diagnostic potential of Fourier-transform infrared (FTIR) spectroscopy combined with machine learning for the detection of ovarian, bowel, and peritoneal endometriosis. The Boruta algorithm was applied to …
To investigate the mechanism of medicinal cake-separated moxibustion in inhibiting the adhesion, invasion and angiogenesis of ectopic endometriotic tissues in endometriosis (EMs) rats through transforming growth factor-β1 (TGF-β)/Sma and Mad …
Can a serum miRNA signature serve as a potential diagnostic biomarker for endometriosis (END)?
Adenomyosis and endometriosis are hormone-dependent benign gynecological disorders with overlapping features suggesting that they may share a common origin despite being considered distinct entities. This study compares the expression of …
Objective: The primary goal of treatment for endometriosis (EMS), where pelvic pain is the most significant symptom, is the symptom alleviation. Medical treatment is typically employed until menopause or until …
Adenomyosis occurs when endometrial glands and stroma grow within the uterine myometrium. As a clinically significant disease, adenomyosis causes substantial pelvic pain and heavy menstrual bleeding. It remains understudied due …