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From Endometriosis to Lipedema: Toward a Neuroimmune Framework for Pain Amplification in Hormone-Sensitive Disorders.

Background: Endometriosis and lipedema are chronic female-predominant disorders characterized by persistent pain that is frequently disproportionate to anatomical lesion burden. Although traditionally interpreted within distinct lesion-centered frameworks, both conditions exhibit …

Published: July 3, 2026, midnight
Integrating the Central Sensitization Inventory (CSI) into Neuropelveological Practice: A Systematic Review of Endometriosis and Overlapping Pelvic Pain Syndromes.

Background: The surgical management of chronic pelvic pain (CPP), particularly in endometriosis, often focuses on lesion excision or nerve decompression. However, persistent pain frequently occurs despite "anatomical perfection," suggesting central …

Published: July 2, 2026, midnight
Interactions Between Neurotrophins and Ovarian Steroids in Endometriosis and Their Implications for Neuroangiogenesis: A Narrative Review.

Endometriosis is a long-term gynecological condition marked by the growth of endometrial-like tissue outside the uterus, which undergoes proliferation, bleeding, and regeneration. This disease is associated with disrupted steroid hormone …

Published: June 24, 2026, midnight
Postoperative and long-term outcomes of nerve-sparing segmental rectal resection and complete nodular resection of rectal endometriosis.

Rectal endometriosis is a severe form of deep endometriosis affecting up to 12% of patients, causing significant pain and bowel dysfunction. The optimal surgical approach can be individually tailored based …

Published: June 23, 2026, midnight
Interleukin-17A as a key driver for cell migration, proliferation, inflammation, and nerve infiltration in deep endometriosis.

Deep endometriosis (DE) is the most severe subtype of endometriosis, marked by aggressive cellular behavior and debilitating pain. However, the molecular mechanisms underlying DE pathogenesis remain poorly understood. In this …

Published: June 15, 2026, midnight
Neurovascular architecture of deep endometriosis and postoperative pain outcomes after butterfly peritoneal excision, a prospective pilot study.

To evaluate the neurovascular architecture of deep endometriosis using a standardized butterfly excision approach and to explore its association with postoperative pain outcomes.

Published: June 7, 2026, midnight
Deep Dyspareunia One Year After Nerve-Sparing Endometriosis Surgery: An Observational Study Highlighting Undesirable Outcomes.

Background/Objectives: This study evaluates the 1-year follow-up outcomes after minimally invasive nerve-sparing surgery for the complete excision of deep endometriosis (DE), with a specific focus on deep dyspareunia. Cases with …

Published: June 5, 2026, midnight
Pelvic neurovascular anatomy and avascular spaces: a pictorial essay of key surgical landmarks.

A precise understanding of pelvic neurovascular anatomy is essential for minimizing complications during advanced gynecological and pelvic surgery. Retroperitoneal dissection requires a clear appreciation of spatial relationships between vascular, neural, …

Published: June 3, 2026, midnight
Inside the obturator canal: robotic ganglion cyst decompression.

Obturator nerve compression is an uncommon cause of groin and medial thigh pain. Ganglion cysts extending into the obturator foramen are rare and usually managed via open or orthopaedic approaches. …

Published: June 2, 2026, midnight
Efficacy and safety of laparoscopic nerve decompression for neuropathic sciatic pain due to endometriosis: A systematic review and meta-analysis.

Endometriosis is associated with neuropathic pain in approximately 40% of cases. Involvement of the sciatic nerve or sacral plexus represents one of the most frequently reported neuropathic pain presentations in …

Published: May 27, 2026, midnight
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