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AURKA inhibits the decidualization of the eutopic endometrium in endometriosis through NF-κB p65†.

Endometriosis is an estrogen dependent disease, which is related to infertility. Decidualization is a prerequisite for successful implantation of human embryos, and endometriosis affects the occurrence of decidualization. However, the …

Published: Dec. 3, 2024, midnight
Overexpressed nicotinamide N‑methyltransferase in endometrial stromal cells induced by macrophages and estradiol contributes to cell proliferation in endometriosis.

Endometriosis, an estrogen-dependent chronic inflammatory condition, afflicts reproductive-aged women. However, the underlying pathological mechanisms remain to be elucidated. Nicotinamide N-methyltransferase (NNMT) is a critical enzyme involved in cellular metabolism and …

Published: Nov. 3, 2024, midnight
Recent progress in metabolomics for analyzing common infertility conditions that affect ovarian function.

Numerous efforts have been undertaken to identify biomarkers associated with embryo and oocyte quality to improve the success rate of in vitro fertilization. Metabolomics has gained traction for its ability …

Published: Sept. 30, 2024, midnight
PAK5-mediated PKM2 phosphorylation is critical for anaerobic glycolysis in endometriosis.

P21-activated kinase 5 (PAK5) belongs to the PAK-II subfamily, which is an important regulator of cell survival, adhesion, and motility. However, the functions of PAK5 in endometriosis remain unclear. Here, …

Published: Sept. 27, 2024, midnight
Correction: Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis.

Published: July 2, 2024, midnight
Phosphorylation of IDH1 Facilitates Progestin Resistance in Endometrial Cancer - Li - 2024 - Advanced Science - Wiley Online Library

Phosphorylation of IDH1 Facilitates Progestin Resistance in Endometrial Cancer - Li - 2024 - Advanced Science Wiley Online Library

Published: April 6, 2024, 7 a.m.
Phosphorylation of INF2 by AMPK promotes mitochondrial fission and oncogenic function in endometrial cancer - Nature.com

Phosphorylation of INF2 by AMPK promotes mitochondrial fission and oncogenic function in endometrial cancer Nature.com

Published: Jan. 17, 2024, 8 a.m.
Exosomes from the Uterine Cavity Mediate Immune Dysregulation via Inhibiting the JNK Signal Pathway in Endometriosis.

Endometriosis is a chronic inflammatory disease with an uncertain pathogenesis. Peritoneal immune dysregulation plays an important role in the pathogenesis of endometriosis. Exosomes are messengers of intercellular communication. This study …

Published: Dec. 2, 2022, midnight
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