NRF2 Signalling in Endometriosis: A Hormone-Independent Axis for Fertility-Preserving Therapeutic Innovation.
Endometriosis is a chronic inflammatory disease characterised by pain, infertility and recurrence. Current pharmacological management relies largely on hormonal suppression, which can reduce pain and disease activity but does not …
Self-reported fertility problems and their socio-demographic and health correlates: a cross-sectional online survey of 8000 Polish adults.
While biological and lifestyle determinants of reproductive health are well documented globally, comprehensive data integrating socio-demographic, lifestyle, and health correlates within a contemporary Polish context remain limited. This study aimed …
GREB1 as a Context-Dependent Molecular Switch in Endometrial Estrogen-Progesterone Crosstalk: From Physiological Receptivity to Endometriosis Pathogenesis-A Narrative Review.
In this narrative review, we summarize current evidence regarding the endometrium undergoes cyclic remodeling driven by estrogen (E2) and progesterone (P4) signaling, with precise coordination essential for receptivity and pregnancy …
The hidden impacts of endocrine-disrupting chemicals on endometrial and pregnancy health.
Endocrine-disrupting chemicals (EDCs) are ubiquitous environmental contaminants that interfere with hormone signalling and are increasingly linked to adverse reproductive outcomes. This viewpoint highlights emerging evidence that EDC exposure disrupts both …
Histological diagnosis of endometriosis and adenomyosis in relation to obstetric outcomes: a Dutch population-based cohort study.
To assess the prevalence of obstetric and neonatal complications in pregnancies of women with histologically confirmed endometriosis, adenomyosis, or both, compared with the general Dutch population.
Response to the letter regarding "Spontaneous pregnancy following intra-ovarian platelet-rich plasma administration in poor ovarian responders according to the POSEIDON criteria: A cross-sectional study".
Oocyte quality in endometriosis-associated infertility: a narrative analysis of mechanisms and therapeutic options.
Endometriosis is a challenging gynaecological condition that can lead to infertility. This unique narrative review summarises the impact of endometriosis, focusing on oocyte quality, its subcellular and molecular mechanisms, clinical …
Diagnosis and Management of Chronic Endometritis: Effects on Postoperative Pregnancy Outcomes in Endometriosis Patients with Proximal Tubal Obstruction Undergoing Hysteroscopic Tubal Catheterization and Laparoscopy.
Background: This study aims to investigate the impact of chronic endometritis (CE) diagnosis and treatment on pregnancy outcomes during hysteroscopic fallopian tube catheterization combined with laparoscopy in infertility patients with …