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Design and implementation of interventions to improve sexual health of women with endometriosis: A mixed-methods study protocol with an interventional design.

Endometriosis has potential negative effects on the fertility, mental, and sexual health of women. Since the conducted studies have not comprehensively addressed the needs and strategies to improve sexual health, …

Published: June 2, 2026, midnight
Safety evaluation of a novel progesterone vaginal ring (PVR) for luteal phase support: SARA trial.

After manufacturing changes, the safety and tolerability of the progesterone vaginal ring (PVR) was compared to findings from the similarly designed phase 3 trial. This prospective, open-label, single-arm, multi-center U.S. …

Published: May 29, 2026, midnight
Effectiveness of an anti-inflammatory diet intervention and cognitive behavioural therapy in endometriosis: protocol for a randomised controlled clinical trial.

Treatment for women with endometriosis is only partially or temporarily effective. Moreover, medical hormonal treatment is associated with debilitating side effects and interferes with fertility, while surgery has a relatively …

Published: May 26, 2026, midnight
ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol.

Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptions hinder effective management, particularly …

Published: May 21, 2026, midnight
Turning Challenges into Success: Successful Pregnancy in Advanced Maternal Age with Adenomyosis Using Prolonged GnRH Agonist Protocol: A Case Report.

Advanced maternal age (AMA) is a major challenge in reproductive medicine, compounded by coexisting conditions such as adenomyosis and endometriosis, which impair oocyte competence and endometrial receptivity. Prolonged gonadotropin-releasing hormone …

Published: May 19, 2026, midnight
Efficacy of different pretreatments in IVF outcomes in patients with endometriosis: A systematic review and network meta‑analysis.

To investigate the efficacy of different pretreatment protocols for women with endometriosis undergoing IVF. We systematically searched the Cochrane Library, PubMed, Medline, and Embase from inception to April 30, 2025, …

Published: May 18, 2026, midnight
Diverging guidelines and consensus statements on preimplantation genetic testing for aneuploidy: indications and strategies reviewed.

Preimplantation genetic testing for aneuploidy (PGT-A) is widely used to screen for embryo aneuploidy, enabling the selection and transfer of genetically normal embryos. Despite its potential to improve clinical outcomes, …

Published: May 7, 2026, midnight
A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions.

Current models of endometriosis (EMs) still have limitations in replicating the key pathological features of human EMs, particularly the cyclic bleeding associated with ectopic lesions. To address this gap, this …

Published: May 6, 2026, midnight
Current methods and mechanisms for animal models of pelvic inflammatory disease: a review.

Pelvic inflammatory disease (PID) is a complex multifactorial infectious disorder of the female reproductive tract, associated with severe long-term sequelae including infertility, ectopic pregnancy, and chronic pelvic pain, as well …

Published: May 1, 2026, midnight
Benefits of minimal ethanol volume and retention without removal in transvaginal ethanol sclerotherapy for endometriomas.

This study aims to introduce an effective protocol for transvaginal ethanol sclerotherapy, focussing on the aspiration of viscous cystic content and the amount of ethanol instilled in the cystic cavity …

Published: April 29, 2026, midnight
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