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Endometriosis and Reproductive Sparing Surgery: A Narrative Review and AGREE II-S-Based Evaluation of International Guidelines.

Endometriosis is a complex disease that may affect a woman's fertility and quality of life. Owing to substantial variations in symptom severity, lesion distribution, and reproductive impact, its management presents …

Published: Jan. 4, 2026, midnight
Quantifying inflammatory resolution in human menstruation reveals disease-specific failure modes and enables a non-invasive diagnostic for endometriosis.

Inflammatory resolution is essential for tissue health, yet its dynamics remain difficult to study in humans. Menstruation is a recurrent, non-pathological inflammatory process that provides a natural window into inflammation …

Published: Jan. 4, 2026, midnight
Rectosigmoid Endometrioma Mimicking Rectal Hematoma: A Diagnostic Dilemma Managed Conservatively.

Endometriosis is a benign gynecological condition characterized by the presence of functional endometrial tissue outside the uterine cavity. Although it most commonly affects pelvic organs, bowel involvement is uncommon, and …

Published: Dec. 31, 2025, midnight
Clinical Effectiveness and Cost-Effectiveness of Misoprostol in Comparison to Dilatation and Curettage for Treatment of First-Trimester Missed Abortion (Gestational Age ≤ 14 Weeks) in Iran.

The development of prostaglandins and antiprogestins revolutionized medical abortion by providing effective nonsurgical options for terminating pregnancy. Although both strategies are accepted in practice, variations in clinical efficacy, patient experiences, …

Published: Dec. 17, 2025, midnight
Borderline ovarian clear cell tumor arising from endometriosis during long-term dienogest therapy: a case report.

Endometriomas, commonly known as ovarian chocolate cysts, are a prevalent condition in women of reproductive age. They are cysts formed by the ectopic growth of endometrial tissue within the ovary, …

Published: Dec. 17, 2025, midnight
Is surgery for endometriomas ever indicated?

Endometriomas can be managed through various approaches, including careful observation, medical suppressive therapy, or surgical intervention. Malignancy is rarely a concern in women of reproductive age, making pain relief and …

Published: Dec. 15, 2025, midnight
Surgical Complexity, Disease Severity, and Direct Healthcare Costs of Endometriosis in the Brazilian Public Health System: A Cross-Sectional Analysis.

The objective was to evaluate the clinical and demographic characteristics of patients undergoing endometriosis surgery in the public healthcare system, estimate the direct costs related to low- and high-complexity procedures, …

Published: Dec. 8, 2025, midnight
Appendiceal endometriosis: an uncommon manifestation of deep infiltrating endometriosis.

Appendiceal endometriosis is a rare cause of acute appendicitis, accounting for approximately 1% of cases.This report describes a case of a female patient presenting with right iliac fossa pain and …

Published: Nov. 26, 2025, midnight
Efficacy of Dienogest Versus GnRH Agonists After Endometriosis Surgery: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis compared the efficacy of dienogest (DNG) and gonadotropin-releasing hormone (GnRH) agonists in the management of endometriosis-related symptoms following surgical intervention, their related adverse effects, and …

Published: Nov. 22, 2025, midnight
Acute Hemoperitoneum Secondary to Chronic Hematosalpinx: A Diagnostic Challenge in the Setting of a Negative Pregnancy Test.

Acute hemoperitoneum represents a gynecological and surgical emergency with significant morbidity if diagnosis and intervention are delayed. In women of reproductive age, the etiology is most frequently ruptured ectopic pregnancy; …

Published: Nov. 20, 2025, midnight
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