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CHRONIC OVERLAPPING PAIN CONDITIONS IN REFRACTORY UROLOGIC CHRONIC PELVIC PAIN SYNDROME (UCPPS):COMORBIDITY PATTERNS, ILLNESS BURDEN, AND TREATMENT IMPLICATIONS.

To examine Chronic Overlapping Pain Conditions (COPC) prevalence in Urologic Chronic Pelvic Pain Syndrome (UCPPS) patients and assess the independent contributions of specific COPCs and pairwise COPC combinations to severity …

Published: Sept. 21, 2026, midnight
How is the "most bothersome symptom" construct measured across health conditions? A systematic review of patient-reported outcome measures.

Patient-reported outcome measures (PROMs) capture patients' experiences and perspectives of symptoms. One approach involves measuring the "most bothersome symptom," an outcome recommended in some regulatory guidance and core outcome sets. …

Published: Sept. 20, 2026, midnight
Neuroimmune fitness in endometriosis: decoding the adaptive neural circuits that sustain lesion persistence, fibrosis, and chronic pain.

Endometriosis is a chronic inflammatory disease characterized by substantial heterogeneity in pain, lesion behavior, and treatment response. Although hormonal and surgical therapies can reduce disease activity and symptoms, their effects …

Published: Sept. 19, 2026, midnight
Mediterranean Diet Adherence and Endometriosis Symptoms: Implications for Nutritional Management.

Endometriosis is a chronic inflammatory disease significantly impairing quality of life (QoL). While the Mediterranean diet (MD) may modulate inflammation, evidence regarding its relationship with symptom burden is limited. This …

Published: Sept. 18, 2026, midnight
Self-Reported Experiences of Women Taking Hormonal Treatments for Their Endometriosis and Uterine Fibroids Symptoms: Results from a Real-World Study in the US (MyEndoUF).

To characterize the experiences of individuals taking hormonal therapies to manage their symptoms of endometriosis (EM) or uterine fibroids (UF).

Published: Sept. 17, 2026, midnight
Risk factors for intraoperative adhesion in ovarian endometriosis patients: A retrospective study.

Endometriosis is a common gynecological disease that can cause pelvic adhesions. Severe adhesions increase the difficulty of surgery, resulting in prolonged operation time, increased intraoperative bleeding, and increased complications such …

Published: Sept. 16, 2026, midnight
Aetiology of pelvic neuropathies in women: a narrative review.

Pelvic neuropathy is an under-recognised contributor to chronic pelvic pain in women, yet a structured overview of its identifiable causes has been lacking. In this narrative review we searched PubMed, …

Published: Sept. 16, 2026, midnight
Functional outcomes after laparoscopic colorectal resection with natural orifice specimen extraction and conventional specimen extraction for deep endometriosis: a 24-month prospective cohort study.

To assess changes in bowel function, pain symptoms, and endometriosis-related quality of life over 24 months after laparoscopic colorectal resection with natural orifice specimen extraction (NOSE) and conventional abdominal specimen …

Published: Sept. 15, 2026, midnight
NRF2 Signalling in Endometriosis: A Hormone-Independent Axis for Fertility-Preserving Therapeutic Innovation.

Endometriosis is a chronic inflammatory disease characterised by pain, infertility and recurrence. Current pharmacological management relies largely on hormonal suppression, which can reduce pain and disease activity but does not …

Published: Sept. 14, 2026, midnight
Presumed Hippocampal Endometriosis Presenting as Catamenial Epilepsy: Diagnostic Challenges, MRI Follow-Up, and Comparative Review of Reported Cerebral Endometriosis Case.

Background: Cerebral endometriosis is an exceptionally rare manifestation of extrapelvic endometriosis and remains a diagnostic challenge because its clinical and imaging features may mimic more common neurological, inflammatory, vascular, or …

Published: Sept. 11, 2026, midnight
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