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Biotechnological progresses in modelling the human endometrium: the evolution of current in vitro techniques and emerging trends.

The endometrium plays a fundamental role in the reproductive system yet many etiologies of infertility-related endometrial diseases such as endometriosis, adenomyosis, Asherman's syndrome or endometrial cancer remain unknown. There are …

Published: Dec. 3, 2024, midnight
Human-AI collaborative multi-modal multi-rater learning for endometriosis diagnosis.

Endometriosis, affecting about 10% of individuals assigned female at birth, is challenging to diagnose and manage. Diagnosis typically involves the identification of various signs of the disease using either laparoscopic …

Published: Dec. 2, 2024, midnight
Environmental Exposure to Per- and Polyfluorylalkyl Substances (PFASs) and Reproductive Outcomes in the General Population: A Systematic Review of Epidemiological Studies.

This Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) systematic review synthesized effects of background levels of per- and polyfluorylalkyl substance (PFAS) levels on reproductive health outcomes in the …

Published: Dec. 2, 2024, midnight
Amygdalin inhibits endometrial stromal cell proliferation, migration, and invasion in endometriosis mice via inhibiting Wnt/β-catenin signaling.

To explore the impact of amygdalin on the proliferation, migration, and invasion of human endometrial stromal cells (HESCs) and the possible underlying mechanism. HESCs were incubated with 50, 100, and …

Published: Nov. 29, 2024, midnight
Unraveling the complexity of follicular fluid: insights into its composition, function, and clinical implications.

Follicular fluid (FF) plays a vital role in the bidirectional communication between oocytes and granulosa cells (GCs), regulating and promoting oocyte growth and development. This fluid constitutes a complex microenvironment, …

Published: Nov. 26, 2024, midnight
Multi-locus high-risk alleles association from interleukin's genes with female infertility and certain comorbidities.

Objective There is evidence that cytokine genes' single nucleotide polymorphisms could be the reasons behind female infertility. This study aimed to identify the role for Interleukin33 rs1048274 (G > A) …

Published: Nov. 23, 2024, midnight
The gut-reproductive axis: Bridging microbiota balances to reproductive health and fetal development.

The gut microbiota is a highly complex microbial community residing in the digestive tract of humans and animals, closely linked to host health. Dysbiosis within the gut microbiota has been …

Published: Nov. 22, 2024, midnight
A Cost-Effectiveness Analysis of Gonadotropins Used for Ovarian Stimulation during Assisted Reproductive Technology Based on Data from the French Nationwide Claims Database (SNDS).

Various gonadotropins are used for ovarian stimulation (OS). This study investigated the cost-effectiveness of different gonadotropins based on real-world data from the French National Health Database (SNDS) over a 7-year …

Published: Nov. 19, 2024, midnight
The Physicians Committee Urges Congress to Deny A $30 Million Expansion of Nonhuman Primate Infrastructure at NIH - Physicians Committee for Responsible Medicine

The Physicians Committee Urges Congress to Deny A $30 Million Expansion of Nonhuman Primate Infrastructure at NIH Physicians Committee for Responsible Medicine

Published: Nov. 14, 2024, 7:40 p.m.
Interrelation Between Pathoadaptability Factors and Crispr-Element Patterns in the Genomes of Escherichia coli Isolates Collected from Healthy Puerperant Women in Ural Region, Russia.

Escherichia coli is a commensal and opportunistic bacterium widely distributed around the world in different niches including intestinal of humans and animals, and its extraordinary genome plasticity led to the …

Published: Nov. 14, 2024, midnight
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