Globally, endometriosis affects almost 10% of reproductive-aged women, leading to chronic pain and discomfort. Endocrine-disrupting compounds (EDCs) seem to play a pivotal role as a causal factor. The current manuscript …
Endometriosis significantly impacts fertility through complex mechanisms. These include chronic inflammation, oxidative stress, and anatomical distortion. These mechanisms impair oocyte quality, embryo development, and implantation. While in vivo challenges persist, …
To analyse levels of reactive oxygen species (ROS) in follicular fluid in patients with endometrioma, and determine their effect on embryo quality and other relevant influencing factors in in-vitro fertilization …
Organ functions generally decline with age, but the ovary is a prototypical organ that undergoes functional loss over time. Autophagy plays a crucial role in maintaining organ homeostasis, and age-related …
Dr explains: How air pollution, stress and late pregnancies are fuelling India's fertility crisis Firstpost
Sulforaphane Alleviates PACS 2-Mediated Oxidative Stress Damage in Porcine Endometrial Stromal Cells Induced by Zearalenone ACS Publications
Taurine alleviates oxidative stress, inflammation, and mitochondrial apoptosis in lipopolysaccharide-induced bovine endometrial epithelial cells by activating Nrf2/HO-1 and inhibiting TLR4-MAPK/NF-κB and Caspase-3 pathways ScienceDirect.com
While obesity has been associated with poor reproductive outcomes, the specific factors affecting gametes remain unclear. Our primary objective was to assess the relationship between a couple's pre-pregnancy body mass …
The adenosine monophosphate (AMP)-activated protein kinase (AMPK) signalling pathway regulates cell metabolism, inflammation and the immune response. This signalling pathway is essential for maintaining reproductive homeostasis and influencing steroidogenesis, implantation, …
Endometriosis and high-grade serous ovarian cancer (HGS-OC) share common features within the peritoneal immune microenvironment, yet they exhibit divergent clinical outcomes. This study aimed to dissect the immune-metabolic landscape of …