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Reframing Endometriosis: Interplay of NETs, Macrophages, and Lymphocytes at the Crossroads of Disease Progression, Infertility, and Malignant Transformation.

Endometriosis (ENDO) is a painful, chronic gynecological disease widely affecting women globally. While traditionally classified as a hormonal disorder, ENDO is now increasingly recognized as a multifaceted immune-mediated syndrome driven …

Published: Oct. 29, 2025, midnight
Integrated Bioinformatics and Experimental Analysis Revealed Crosstalk Between IL-6, Autophagy, Ubiquitination, and Key miRNAs in Female Infertility: Insights from Ovarian Endometriosis and Polycystic Ovary Syndrome.

Female infertility, affecting millions worldwide, involves complex molecular mechanisms such as chronic inflammation, impaired cellular death, and protein regulation. This study explores how the cytokine IL-6, the autophagy marker LC3, …

Published: Oct. 28, 2025, midnight
Case Report: Long-term maintenance of GnRH-a combined with dienogest for thoracic endometriosis syndrome.

Thoracic endometriosis syndrome is a rare form of endometriosis in which endometrial tissue is thought to migrate to the lungs and, with the onset of menstruation, the ectopic foci bleed, …

Published: Oct. 27, 2025, midnight
Pelvic Puzzles: Imaging Non-Traumatic Emergencies of the Female Pelvis: A Comprehensive Review.

Acute non-traumatic pelvic pain represents a frequent and complex diagnostic dilemma in pre-menopausal females presenting to the emergency department due to overlapping symptomatology across pregnancy and non-pregnancy related causes. Radiologists …

Published: Oct. 25, 2025, midnight
Ferroptosis in the Ovarian Follicular Microenvironment: A Redox-Dependent Cell Death Pathway with Emerging Roles in PCOS, Oocyte Quality, and IVF Outcomes.

Ferroptosis is a novel kind of regulated cell death that occurs when redox equilibrium is disrupted, leading to iron-dependent lipid peroxidation. Ferroptosis is defined by the buildup of deleterious lipid …

Published: Oct. 25, 2025, midnight
Targeting Steroid Receptor Coactivators for the Treatment of Benign Female Reproductive Disorders.

Steroid receptor coactivators (SRCs) are master regulators of nuclear receptor signaling and play essential roles in female reproductive physiology. By integrating steroid hormone signaling with growth factors and metabolic pathways, …

Published: Oct. 23, 2025, midnight
Digital Health Technologies in the Treatment of Chronic Pelvic Pain Syndromes: A Systematic Review of Randomized Clinical Trials.

Objective: To comprehensively examine the qualitative results of current studies reporting the efficacy of digital health (DH) technologies in the treatment of chronic pelvic pain syndromes (CPPS) and to describe …

Published: Oct. 22, 2025, midnight
Comparison of sociodemographic factors, lifestyle, and gastrointestinal symptoms between patients with endometriosis and IBS.

Endometriosis and Irritable bowel syndrome (IBS) are two common diseases with overlapping symptomatology, causing confusion and delay in the diagnostic process. The objective of this study was to identify differences …

Published: Oct. 21, 2025, midnight
Shaoyao Gancao Decoction: a comprehensive review of modern clinical applications and underlying pharmacological mechanisms.

Shaoyao Gancao Decoction, a classic formula from Zhang Zhongjing in the Han Dynasty, has the effects of regulating the function of the liver, relieving spasm and stopping pain. Traditionally, it …

Published: Oct. 20, 2025, midnight
Impact of visceral pain on migraine symptoms in comorbid patients: a retrospective observational study.

Visceral pain and migraine, especially at a high frequency/chronic, are frequent comorbidities, but little is known about their mutual influences. This study investigated if visceral pain-migraine comorbidity involves higher migraine …

Published: Oct. 16, 2025, midnight
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